methotrimeprazine

CHEBI:6838 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:32876 CHEBI:32876
CHEBI:38093 CHEBI:38093

Chemical structure

Computed structure properties
Molecular formula	C19H24N2OS
Charge	0
Average mass	328.481 Da
Monoisotopic mass	328.16093 Da
Source	ChEBI
InChIKey	VRQVVMDWGGWHTJ-CQSZACIVSA-N

SMILES

COc1ccc2c(c1)N(C[C@H](C)CN(C)C)c1ccccc1S2

InChI

InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m1/s1

Also called

levomepromazina (INN)— chebi
levomepromazine (INN)— chebi
levomepromazinum (INN)— chebi
lévomépromazine (INN)— chebi
(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (EXACT_SYNONYM)— chebi
(-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (EXACT_SYNONYM)— chebi
(-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine (EXACT_SYNONYM)— chebi
2-Methoxytrimeprazine (EXACT_SYNONYM)— chebi
Levomepromazine (EXACT_SYNONYM)— chebi
Methotrimeprazine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:60-99-1
drugbank:DB01403
drugcentral:1752
hmdb:HMDB0015474
kegg.compound:C07192
kegg.drug:D00403
kegg.drug:D06474
lincs.smallmolecule:LSM-2778
patent:US2837518
reaxys:92434
wikipedia.en:Levomepromazine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:149553 CHEBI:149553

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:6838`	methotrimeprazine	`antibioticmech:chebi-7198be7765`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.