mycophenolate mofetil

CHEBI:8764 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:25698 CHEBI:25698
CHEBI:33308 CHEBI:33308
CHEBI:33853 CHEBI:33853
CHEBI:37581 CHEBI:37581
CHEBI:50996 CHEBI:50996

Chemical structure

Computed structure properties
Molecular formula	C23H31NO7
Charge	0
Average mass	433.501 Da
Monoisotopic mass	433.21005 Da
Source	ChEBI
InChIKey	RTGDFNSFWBGLEC-SYZQJQIISA-N

SMILES

COc1c(C)c2c(c(O)c1C/C=C(\C)CCC(=O)OCCN1CCOCC1)C(=O)OC2

InChI

InChI=1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+

Also called

Cellcept (BRAND_NAME)— chebi
2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate (EXACT_SYNONYM)— chebi
2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate (EXACT_SYNONYM)— chebi
MMF (EXACT_SYNONYM)— chebi
RS 61443 (EXACT_SYNONYM)— chebi
mycophenolic acid morpholinoethyl ester (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:128794-94-5
drugbank:DB00688
drugcentral:1859
hmdb:HMDB0014826
kegg.compound:C07908
kegg.drug:D00752
reaxys:7500599
wikipedia.en:Mycophenolate_mofetil

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:149553 CHEBI:149553

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:8764`	mycophenolate mofetil	`antibioticmech:chebi-815ebc1095`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.