N-(2-aminoethyl)-1-aziridine-ethanamine

CHEBI:145998 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A primary amino compound that is ethane-1,2-diamine in which the hydrogen on one of the amino groups is replaced by a 2-(aziridin-1-yl)ethyl group. It is a angiotensin-converting enzyme 2 (ACE2) inhibitor and a potential therapeutic agent for treating SARS coronavirus infections. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:22681 CHEBI:22681
CHEBI:50994 CHEBI:50994
CHEBI:50995 CHEBI:50995

Chemical structure

Computed structure properties
Molecular formula	C6H15N3
Charge	0
Average mass	129.207 Da
Monoisotopic mass	129.1266 Da
Source	ChEBI
InChIKey	XJNAQZHMIAKQOK-UHFFFAOYSA-N

SMILES

NCCNCCN1CC1

InChI

InChI=1S/C6H15N3/c7-1-2-8-3-4-9-5-6-9/h8H,1-7H2

Also called

N-[2-(aziridin-1-yl)ethyl]ethane-1,2-diamine (EXACT_SYNONYM)— chebi
N-(2-((2-aminoethyl)amino)ethyl)aziridine (EXACT_SYNONYM)— chebi
N-(2-aminoethyl)-1 aziridine-ethanamine (EXACT_SYNONYM)— chebi
N-(2-aminoethyl)-1-aziridineethanamine (EXACT_SYNONYM)— chebi
N1-(2-(1-aziridinyl)ethyl)-1,2-ethanediamine (EXACT_SYNONYM)— chebi
N1-[2-(aziridin-1-yl)ethyl]ethane-1,2-diamine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:23435-23-6

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:149553 CHEBI:149553

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:145998`	N-(2-aminoethyl)-1-aziridine-ethanamine	`antibioticmech:chebi-3871e25c2c`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.