N2-methylharmine
CHEBI:66005
·resolve ·ANTIVIRAL
·EXACT
SEEDED
A member of the class of β-carbolines that is 9H-β-carboline substituted by a methoxy group at position 7 and methyl groups at positions 1 and 2. It is a semisynthetic derivative of harmine and has been shown to exhibit significant anti-HIV activity. — ChEBI
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | C14H14N2O |
|---|
| Charge | 0 |
|---|
| Average mass | 226.279 Da |
|---|
| Monoisotopic mass | 226.11061 Da |
|---|
| Source | ChEBI |
|---|
| InChIKey | SNPOLGTUMADPOR-UHFFFAOYSA-N |
|---|
SMILES
COc1ccc2c3ccn(C)c(C)c-3nc2c1
InChI
InChI=1S/C14H14N2O/c1-9-14-12(6-7-16(9)2)11-5-4-10(17-3)8-13(11)15-14/h4-8H,1-3H3
Also called
- 7-methoxy-1,2-dimethyl-2H-β-carboline (EXACT_SYNONYM)— chebi
- 7-methoxy-1,2-dimethyl-2H-pyrido[3,4-b]indole (EXACT_SYNONYM)— chebi
Cross-references
Equivalent identifiers for this same structure in other resources.
Activity roles
Every antimicrobial role a source asserts for this compound — the
unreduced evidence behind its antimicrobial_class.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| CHEBI |
CHEBI:66005 |
N2-methylharmine |
antibioticmech:chebi-75dc625ca2 |
2026-08-30 |
Curation history
-
SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.