niclosamide

CHEBI:7553 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:140325
Label unavailable CHEBI:22702
Label unavailable CHEBI:35716
Label unavailable CHEBI:53468
Label unavailable CHEBI:83403

Chemical structure

Computed structure properties
Charge
Source	ChEBI
InChIKey	RJMUSRYZPJIFPJ-UHFFFAOYSA-N

SMILES

O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O

InChI

InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)

Also called

Atenase (BRAND_NAME)— chebi
Bayluscide (BRAND_NAME)— chebi
Cestocid (BRAND_NAME)— chebi
Devermin (BRAND_NAME)— chebi
Devermine (BRAND_NAME)— chebi
Fedal-Telmin (BRAND_NAME)— chebi
Fenasal (BRAND_NAME)— chebi
Helmiantin (BRAND_NAME)— chebi
Iomesan (BRAND_NAME)— chebi
Lintex (BRAND_NAME)— chebi
Mansonil (BRAND_NAME)— chebi
Mato (BRAND_NAME)— chebi
Nasemo (BRAND_NAME)— chebi
Niclocide (BRAND_NAME)— chebi
Phenasal (BRAND_NAME)— chebi
Radeverm (BRAND_NAME)— chebi
Sagimid (BRAND_NAME)— chebi
Sulqui (BRAND_NAME)— chebi
Tredemine (BRAND_NAME)— chebi
Utosamide (BRAND_NAME)— chebi
Vermitid (BRAND_NAME)— chebi
Vermitin (BRAND_NAME)— chebi
Yomesan (BRAND_NAME)— chebi
Zestocarp (BRAND_NAME)— chebi
niclosamida (INN)— chebi
niclosamidum (INN)— chebi
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (EXACT_SYNONYM)— chebi
2',5-dichloro-2-hydroxy-4'-nitrobenzanilide (EXACT_SYNONYM)— chebi
2',5-dichloro-4'-nitrosalicylanilide (EXACT_SYNONYM)— chebi
2-chloro-4-nitrophenylamide-6-chlorosalicylic acid (EXACT_SYNONYM)— chebi
2-hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide (EXACT_SYNONYM)— chebi
5-chloro-2'-chloro-4'-nitrosalicylanilide (EXACT_SYNONYM)— chebi
5-chloro-N-(2'-chloro-4'-nitrophenyl)salicylamide (EXACT_SYNONYM)— chebi
B 2353 (EXACT_SYNONYM)— chebi
BAY 2353 (EXACT_SYNONYM)— chebi
Bayer 2353 (EXACT_SYNONYM)— chebi
Bayer 73 (EXACT_SYNONYM)— chebi
HL 2447 (EXACT_SYNONYM)— chebi
N-(2'-chloro-4'-nitrophenyl)-5-chlorosalicylamide (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

wikipedia.en:Niclosamide

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

anticoronaviral agent CHEBI:149553

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:7553`	niclosamide	`antibioticmech:chebi-7499d35beb`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-02 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-06 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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