promethazine hydrochloride

CHEBI:8462 ·resolve ·ANTIVIRAL ·EXACT SEEDED

The hydrochloride salt of promethazine. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:36807

Chemical structure

Computed structure properties
Molecular formula	C17H20N2S.HCl
Charge	0
Average mass	320.889 Da
Monoisotopic mass	320.1114 Da
Source	ChEBI
InChIKey	XXPDBLUZJRXNNZ-UHFFFAOYSA-N

SMILES

CC(CN1c2ccccc2Sc2ccccc21)N(C)C.Cl

InChI

InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H

Also called

Fenergan (BRAND_NAME)— chebi
Phenergan (BRAND_NAME)— chebi
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride (EXACT_SYNONYM)— chebi
(+-)-10-(2-(Dimethylamino)propyl)phenothiazine monohydrochloride (EXACT_SYNONYM)— chebi
10-(2-Dimethylamino-1-propyl)phenothiazine hydrochloride (EXACT_SYNONYM)— chebi
10-(3-Dimethylaminoisopropyl)phenothiazine hydrochloride (EXACT_SYNONYM)— chebi
N-(2'-dimethylamino-2'-methyl)ethylphenothiazine hydrochloride (EXACT_SYNONYM)— chebi
N-(2-dimethylaminopropyl-1)phenothiazine hydrochloride (EXACT_SYNONYM)— chebi
promethazine HCl (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

cas:58-33-3
reaxys:4166397

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

anticoronaviral agent CHEBI:149553

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:8462`	promethazine hydrochloride	`antibioticmech:chebi-704dbdd41b`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (promethazine hydrochloride) · CultureMech · NaturalProductMech · PathwayMech · TraitMech