AntibioticMech

tiratricol

CHEBI:40021 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A monocarboxylic acid that is (4-hydroxy-3,5-diiodophenyl)acetic acid in which the phenolic hydroxy group has been replaced by a 4-hydroxy-3-iodophenoxy group. It is a thyroid hormone analogue that has been used in the treatment of thyroid hormone resistance syndrome. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:25384 CHEBI:25384
• CHEBI:33853 CHEBI:33853
• CHEBI:35618 CHEBI:35618
• CHEBI:37142 CHEBI:37142

Chemical structure

Computed structure properties

Molecular formula	C14H9I3O4
Charge	0
Average mass	621.934 Da
Monoisotopic mass	621.7635 Da
Source	ChEBI
InChIKey	UOWZUVNAGUAEQC-UHFFFAOYSA-N

SMILES

O=C(O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1

InChI

InChI=1S/C14H9I3O4/c15-9-6-8(1-2-12(9)18)21-14-10(16)3-7(4-11(14)17)5-13(19)20/h1-4,6,18H,5H2,(H,19,20)

Also called

• Emcitate (BRAND_NAME)— chebi
• Nidolin (BRAND_NAME)— chebi
• Tiracana (BRAND_NAME)— chebi
• Triax (BRAND_NAME)— chebi
• Téatrois (BRAND_NAME)— chebi
• tiratricolum (INN)— chebi
• [4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid (EXACT_SYNONYM)— chebi
• 2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid (EXACT_SYNONYM)— chebi
• 3,3',5-triiodothyroacetic acid (EXACT_SYNONYM)— chebi
• 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzeneacetic acid (EXACT_SYNONYM)— chebi
• T3A (EXACT_SYNONYM)— chebi
• TRIAC (EXACT_SYNONYM)— chebi
• [(4-hydroxy-3-iodo-4-phenoxy)-3,5-diiodophenyl]acetic acid (EXACT_SYNONYM)— chebi
• triiodothyroacetic acid (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:51-24-1
• drugbank:DB03604
• drugcentral:3611
• kegg.drug:D07214
• lincs.smallmolecule:LSM-5706
• pdb-ccd:4HY
• wikipedia.en:Tiratricol

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:22587 CHEBI:22587

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:40021	tiratricol	antibioticmech:chebi-c34279dade	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.