triflupromazine

CHEBI:9711 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:32876 CHEBI:32876
CHEBI:37143 CHEBI:37143
CHEBI:38093 CHEBI:38093

Chemical structure

Computed structure properties
Molecular formula	C18H19F3N2S
Charge	0
Average mass	352.425 Da
Monoisotopic mass	352.1221 Da
Source	ChEBI
InChIKey	XSCGXQMFQXDFCW-UHFFFAOYSA-N

SMILES

CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21

InChI

InChI=1S/C18H19F3N2S/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21/h3-4,6-9,12H,5,10-11H2,1-2H3

Also called

triflupromazina (INN)— chebi
triflupromazinum (INN)— chebi
N,N-dimethyl-3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propan-1-amine (EXACT_SYNONYM)— chebi
10-(3-(Dimethylamino)propyl)-2-(trifluoromethyl)phenothiazine (EXACT_SYNONYM)— chebi
2-(Trifluoromethyl)promazine (EXACT_SYNONYM)— chebi
2-Trifluoromethyl-10-(gamma-dimethylaminopropyl)phenothiazine (EXACT_SYNONYM)— chebi
trifluopromazine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:146-54-3
drugbank:DB00508
drugcentral:2742
hmdb:HMDB0014650
kegg.drug:D00390
lincs.smallmolecule:LSM-3421
patent:GB813861
reaxys:335308
wikipedia.en:Triflupromazine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:149553 CHEBI:149553

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:9711`	triflupromazine	`antibioticmech:chebi-e741047427`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.