tripterifordin

CHEBI:66275 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A kaurane diterpenoid that is (5β,8α,13α)-18,20-epoxykauran-18-one substituted by a hydroxy group at position 16. Isolated from the roots of Tripterygium wilfordii, it exhibits anti-HIV activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:26878 CHEBI:26878
CHEBI:38164 CHEBI:38164
CHEBI:49193 CHEBI:49193
CHEBI:53666 CHEBI:53666

Chemical structure

Computed structure properties
Molecular formula	C20H30O3
Charge	0
Average mass	318.457 Da
Monoisotopic mass	318.21949 Da
Source	ChEBI
InChIKey	KLMZPLYXGZZBCX-TYOHIEAGSA-N

SMILES

[H][C@@]12CC[C@@]3([H])[C@@](CC[C@@]4([H])[C@]35CCC[C@]4(C)C(=O)OC5)(C1)C[C@]2(C)O

InChI

InChI=1S/C20H30O3/c1-17-7-3-8-20(12-23-16(17)21)14(17)6-9-19-10-13(4-5-15(19)20)18(2,22)11-19/h13-15,22H,3-12H2,1-2H3/t13-,14-,15+,17+,18+,19+,20-/m1/s1

Also called

(5β,8α,13α)-16-hydroxy-18,20-epoxykauran-18-one (EXACT_SYNONYM)— chebi
Kauran-18-oic acid, 16,20-dihydroxy-, delta-lactone,(4alpha)- (EXACT_SYNONYM)— chebi
hypodiolide A (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:139122-81-9
knapsack:C00041947
reaxys:8587307

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:64946 CHEBI:64946

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:66275`	tripterifordin	`antibioticmech:chebi-0c4ddaf1fa`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.