trisodium phosphonoformate
CHEBI:141644
·resolve ·ANTIVIRAL
·EXACT
SEEDED
The trisodium salt of phosphonoformic acid. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity. — ChEBI
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | CO5P.3Na |
|---|
| Charge | 0 |
|---|
| Average mass | 191.95 Da |
|---|
| Monoisotopic mass | 191.91764 Da |
|---|
| Source | ChEBI |
|---|
| InChIKey | DFHAXXVZCFXGOQ-UHFFFAOYSA-K |
|---|
SMILES
O=C([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+]
InChI
InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3
Also called
- foscarnet sodique (INN)— chebi
- foscarnet sodium (INN)— chebi
- foscarneto sodico (INN)— chebi
- foscarnetum natricum (INN)— chebi
- FOSCARNET SODIUM (EXACT_SYNONYM)— chebi
- trisodium carboxyphosphate (EXACT_SYNONYM)— chebi
- trisodium carboxyphosphate (anhydrous) (EXACT_SYNONYM)— chebi
- trisodium dioxidophosphinecarboxylate oxide (EXACT_SYNONYM)— chebi
- trisodium phosphonoformate (anhydrous) (EXACT_SYNONYM)— chebi
Cross-references
Equivalent identifiers for this same structure in other resources.
Activity roles
Every antimicrobial role a source asserts for this compound — the
unreduced evidence behind its antimicrobial_class.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| CHEBI |
CHEBI:141644 |
trisodium phosphonoformate |
antibioticmech:chebi-693752728c |
2026-08-30 |
Curation history
-
SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.