acriflavine
antibioticmech:aro-1fe0873afd
·BIOCIDE
·MINTED
SEEDED
Acriflavine is a topical antiseptic. It has the form of an orange or brown powder. It may be harmful in the eyes or if inhaled. Acriflavine is also used as treatment for external fungal infections of aquarium fish. — PMID:11566977
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
disinfecting agents and antisepticsARO:3005386
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | C27H25ClN6 |
|---|
| Charge | 0 |
|---|
| Average mass | 469.0 Da |
|---|
| Monoisotopic mass | 468.1829225 Da |
|---|
| Source | PubChem · retrieved 2026-08-29 |
|---|
| InChIKey | PEJLNXHANOHNSU-UHFFFAOYSA-N |
|---|
SMILES
C[N+]1=C2C=C(C=CC2=CC3=C1C=C(C=C3)N)N.C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N.[Cl-]
InChI
InChI=1S/C14H13N3.C13H11N3.ClH/c1-17-13-7-11(15)4-2-9(13)6-10-3-5-12(16)8-14(10)17;14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;/h2-8H,1H3,(H3,15,16);1-7H,14-15H2;1H
Also called
- Acriflavin (EXACT_SYNONYM)— aro
- Assiflavine (EXACT_SYNONYM)— aro
- Bialflavina (EXACT_SYNONYM)— aro
- Bioacridin (EXACT_SYNONYM)— aro
- Bovoflavin (EXACT_SYNONYM)— aro
- Buroflavin (EXACT_SYNONYM)— aro
- Choliflavin (EXACT_SYNONYM)— aro
- Euflavine (EXACT_SYNONYM)— aro
- Pantonsiletten (EXACT_SYNONYM)— aro
- Xanthacridinum (EXACT_SYNONYM)— aro
Cross-references
Equivalent identifiers for this same structure in other resources.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| ARO |
ARO:0000045 |
acriflavine |
antibioticmech:aro-1fe0873afd |
2026-08-30 |
Resistance mechanisms
19 known routes by which microbes
resist this compound, grounded in ARO where CARD models them. Grouped by mechanism
type — expand a group to see its determinants.
ANTIBIOTIC_EFFLUX 19
ANTIBIOTIC_EFFLUX
| Determinant | ARO ID | Organism | Gene families | Evidence |
|---|
| Acinetobacter baumannii AmvA |
ARO:3004577 |
not organism-specific |
— |
- ARO:3004577 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| Enterobacter aerogenes acrR with mutation conferring multidrug antibiotic resistance |
ARO:3003374 |
not organism-specific |
— |
- ARO:3003374 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| MdtNOP |
ARO:3004101 |
not organism-specific |
— |
- ARO:3004101 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| MexGHI-OpmD |
ARO:3000799 |
not organism-specific |
— |
- ARO:3000799 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| MexHI-OpmD |
ARO:3009153 |
not organism-specific |
— |
- ARO:3009153 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| MexPQ-OpmE |
ARO:3003697 |
not organism-specific |
— |
- ARO:3003697 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| MexVW-OprM |
ARO:3003029 |
not organism-specific |
— |
- ARO:3003029 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| MexXY-OprM |
ARO:3003032 |
not organism-specific |
— |
- ARO:3003032 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| abeM |
ARO:3000753 |
not organism-specific |
— |
- ARO:3000753 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| acrB |
ARO:3000216 |
not organism-specific |
— |
- ARO:3000216 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| blt |
ARO:3003006 |
not organism-specific |
— |
- ARO:3003006 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| bmr |
ARO:3003007 |
not organism-specific |
— |
- ARO:3003007 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| cdeA |
ARO:3003835 |
not organism-specific |
— |
- ARO:3003835 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| emeA |
ARO:3003551 |
not organism-specific |
— |
- ARO:3003551 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| hmrM |
ARO:3003953 |
not organism-specific |
— |
- ARO:3003953 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| mdeA |
ARO:3007011 |
not organism-specific |
— |
- ARO:3007011 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| mdtM |
ARO:3001214 |
not organism-specific |
— |
- ARO:3001214 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| norA |
ARO:3000391 |
not organism-specific |
— |
- ARO:3000391 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
| sepA |
ARO:3007012 |
not organism-specific |
— |
- ARO:3007012 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:0000045 (acriflavine); database assertion, not a primary citation.)
|
Curation history
-
SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.