1-(hydroxymethyl)-5,5-dimethylhydantoin

CHEBI:143246 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

An imidazolidine-2,4-dione substituted by a hydroxymethyl group at position 1 and two methyl groups at position 5. It is approved by the FDA for use as an adjuvant in the bleaching of recycled paper and board used in food packaging, and is also a decomposition product of DMDM hydantoin, a preservative and antimicrobial agent used in cosmetics and personal care products. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:24628 CHEBI:24628
CHEBI:73080 CHEBI:73080

Chemical structure

Computed structure properties
Molecular formula	C6H10N2O3
Charge	0
Average mass	158.157 Da
Monoisotopic mass	158.06914 Da
Source	ChEBI
InChIKey	SIQZJFKTROUNPI-UHFFFAOYSA-N

SMILES

CC1(C)C(=O)NC(=O)N1CO

InChI

InChI=1S/C6H10N2O3/c1-6(2)4(10)7-5(11)8(6)3-9/h9H,3H2,1-2H3,(H,7,10,11)

Also called

1-(hydroxymethyl)-5,5-dimethylimidazolidine-2,4-dione (EXACT_SYNONYM)— chebi
(5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)methanol (EXACT_SYNONYM)— chebi
(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione (EXACT_SYNONYM)— chebi
1-(hydroxymethyl)-5,5-dimethyl-2,4-imidazolidinedione (EXACT_SYNONYM)— chebi
1-hydroxymethyl-5,5-dimethyl-2,4-imidazolidinedione (EXACT_SYNONYM)— chebi
1-hydroxymethyl-5,5-dimethylhydantoin (EXACT_SYNONYM)— chebi
1-methylol-5,5-dimethylhydantoin (EXACT_SYNONYM)— chebi
1-monomethylol-5,5-dimethylhydantoin (EXACT_SYNONYM)— chebi
5,5-dimethyl-1-(hydroxymethyl)hydantoin (EXACT_SYNONYM)— chebi
5,5-dimethyl-1-(hydroxymethyl)imidazolidine-2,4-dione (EXACT_SYNONYM)— chebi
5,5-dimethyl-1-hydroxymethylhydantoin (EXACT_SYNONYM)— chebi
MDM hydantoin (EXACT_SYNONYM)— chebi
MDMH (EXACT_SYNONYM)— chebi
hydroxymethyl-5,5-dimethylhydantoin (EXACT_SYNONYM)— chebi
methylol dimethylhydantoin (EXACT_SYNONYM)— chebi
monomethylol dimethyl hydantoin (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:116-25-6
cas:27636-82-4
hmdb:HMDB0031670
pubchem.compound:67000
reaxys:139160

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:143246`	1-(hydroxymethyl)-5,5-dimethylhydantoin	`antibioticmech:chebi-2733fe2bab`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.