alborixin

CHEBI:77940 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A polyether antibiotic that is isolated from cultures of a strain of Streptomyces albus. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:25384 CHEBI:25384
CHEBI:26179 CHEBI:26179
CHEBI:26912 CHEBI:26912
CHEBI:59780 CHEBI:59780

Chemical structure

Computed structure properties
Molecular formula	C48H84O14
Charge	0
Average mass	885.186 Da
Monoisotopic mass	884.58611 Da
Source	ChEBI
InChIKey	WWDHGOLBPBWCNJ-GXXSWWTOSA-N

SMILES

[H][C@]1([C@@H](C)C(=O)O)O[C@@H](C[C@@H](O)[C@H](C)[C@@]2([H])CC[C@H](C)[C@@](O)(C[C@H]3O[C@@](O)([C@H](O)[C@]4([H])CC[C@@](C)([C@]5(O)O[C@](C)([C@@]6([H])CC[C@@](C)(O)[C@H](CC)O6)C[C@H]5C)O4)[C@H](C)C[C@@H]3C)O2)[C@H](C)C[C@@H]1C

InChI

InChI=1S/C48H84O14/c1-13-38-43(10,53)18-17-39(58-38)44(11)23-30(7)48(56,62-44)45(12)19-16-35(59-45)41(50)47(55)29(6)21-26(3)37(61-47)24-46(54)28(5)14-15-34(60-46)31(8)33(49)22-36-25(2)20-27(4)40(57-36)32(9)42(51)52/h25-41,49-50,53-56H,13-24H2,1-12H3,(H,51,52)/t25-,26+,27+,28+,29-,30-,31+,32-,33-,34-,35+,36+,37-,38+,39-,40+,41-,43-,44+,45+,46-,47-,48-/m1/s1

Also called

(2R)-2-[(2S,3S,5R,6S)-6-{(2R,3S)-3-[(2R,5S,6R)-6-({(2R,3S,5R,6R)-6-[(R)-{(2S,2'R,3'R,5S,5'S)-5'-[(2R,5R,6S)-6-ethyl-5-hydroxy-5-methyltetrahydro-2H-pyran-2-yl]-2'-hydroxy-2,3',5'-trimethyloctahydro-2,2'-bifuran-5-yl}(hydroxy)methyl]-6-hydroxy-3,5-dimethyltetrahydro-2H-pyran-2-yl}methyl)-6-hydroxy-5-methyltetrahydro-2H-pyran-2-yl]-2-hydroxybutyl}-3,5-dimethyltetrahydro-2H-pyran-2-yl]propanoic acid (EXACT_SYNONYM)— chebi
Antibiotic S 14750A (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:57760-36-8
patent:US4933364
reaxys:6262683

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:77940`	alborixin	`antibioticmech:chebi-749f2e7e7c`	2026-08-30

Mechanism summary

Mode of action: MEMBRANE_DISRUPTION host shared target — Assigned from ChEBI role CHEBI:24869 (ionophore). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.