ansamitocin P3

CHEBI:29515 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A polyketide antibiotic that is isolated from Actinosynnema pretiosum and also exhibits antitumour activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:23003
Label unavailable CHEBI:24995
Label unavailable CHEBI:26188
Label unavailable CHEBI:32955
Label unavailable CHEBI:33308
Label unavailable CHEBI:35618
Label unavailable CHEBI:51026
Label unavailable CHEBI:83403

Chemical structure

Computed structure properties
Molecular formula	C32H43ClN2O9
Charge	0
Average mass	635.154 Da
Monoisotopic mass	634.26571 Da
Source	ChEBI
InChIKey	OPQNCARIZFLNLF-JBHFWYGFSA-N

SMILES

[H][C@@]12O[C@@]1(C)[C@@H](OC(=O)C(C)C)CC(=O)N(C)c1cc(cc(OC)c1Cl)C/C(C)=C/C=C/[C@@H](OC)[C@@]1(O)C[C@]([H])(OC(=O)N1)[C@H]2C

InChI

InChI=1S/C32H43ClN2O9/c1-17(2)29(37)43-25-15-26(36)35(6)21-13-20(14-22(40-7)27(21)33)12-18(3)10-9-11-24(41-8)32(39)16-23(42-30(38)34-32)19(4)28-31(25,5)44-28/h9-11,13-14,17,19,23-25,28,39H,12,15-16H2,1-8H3,(H,34,38)/b11-9+,18-10+/t19-,23+,24-,25+,28+,31+,32+/m1/s1

Also called

(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2-methylpropanoate (EXACT_SYNONYM)— chebi
2'-De(acetylmethylamino)-2'-methylmaytansine (EXACT_SYNONYM)— chebi
Antibiotic C15003P3 (EXACT_SYNONYM)— chebi
C15003P3 (EXACT_SYNONYM)— chebi
Maytansinol isobutyrate (EXACT_SYNONYM)— chebi
ansamitocin P-3 (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

patent:US2007135629

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antimicrobial agent CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:29515`	ansamitocin P3	`antibioticmech:chebi-188600a360`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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