EI-1511-5

CHEBI:65823 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

An epoxide isolated from Streptomyces sp. E-1511. An inhibitor of interleukin-1β converting enzyme (ICE), it acts as an anti-inflammatory agent and an antibiotic. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:26878
Label unavailable CHEBI:29347
Label unavailable CHEBI:32955
Label unavailable CHEBI:33823
Label unavailable CHEBI:3992

Chemical structure

Computed structure properties
Molecular formula	C29H32N2O7
Charge	0
Average mass	520.582 Da
Monoisotopic mass	520.22095 Da
Source	ChEBI
InChIKey	OTILGUINRVYYKM-BSZZVILASA-N

SMILES

[H][C@@]12O[C@]1([H])C(=O)C(NC(=O)/C=C/C=C/C=C/C(C)CC)=C[C@@]2(O)/C=C/C=C/C=C/C(=O)NC1=C(O)CCC1=O

InChI

InChI=1S/C29H32N2O7/c1-3-19(2)12-8-4-5-9-13-23(34)30-20-18-29(37,28-27(38-28)26(20)36)17-11-7-6-10-14-24(35)31-25-21(32)15-16-22(25)33/h4-14,17-19,27-28,32,37H,3,15-16H2,1-2H3,(H,30,34)(H,31,35)/b5-4+,7-6+,12-8+,13-9+,14-10+,17-11+/t19?,27-,28-,29+/m1/s1

Also called

(2E,4E,6E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyldeca-2,4,6-trienamide (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

reaxys:7630198

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antimicrobial agent CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:65823`	EI-1511-5	`antibioticmech:chebi-1baa72c753`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (EI-1511-5) · CultureMech · NaturalProductMech · PathwayMech · TraitMech