erythromycin ethylsuccinate

CHEBI:31555 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A erythromycin derivative that is erythromycin A in which the hydroxy group at position 3R is substituted by a (4-ethoxy-4-oxobutanoyl)oxy group. It is used for the treatment of a wide variety of bacterial infections. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:23990 CHEBI:23990
CHEBI:36181 CHEBI:36181
CHEBI:3992 CHEBI:3992
CHEBI:48924 CHEBI:48924

Chemical structure

Computed structure properties
Molecular formula	C43H75NO16
Charge	0
Average mass	862.064 Da
Monoisotopic mass	861.50859 Da
Source	ChEBI
InChIKey	NSYZCCDSJNWWJL-YXOIYICCSA-N

SMILES

CCOC(=O)CCC(=O)O[C@H]1[C@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)O[C@H](C)C[C@@H]1N(C)C

InChI

InChI=1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,32+,34+,35-,36-,37+,38-,40+,41-,42-,43-/m1/s1

Also called

E-Mycin (BRAND_NAME)— chebi
E-Mycin E (BRAND_NAME)— chebi
E.E.S (BRAND_NAME)— chebi
E.E.S 200 (BRAND_NAME)— chebi
E.E.S 400 (BRAND_NAME)— chebi
EES (BRAND_NAME)— chebi
EryPed (BRAND_NAME)— chebi
Erythroped (BRAND_NAME)— chebi
Pediamycin (BRAND_NAME)— chebi
Wyamycin E (BRAND_NAME)— chebi
(2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (EXACT_SYNONYM)— chebi
erythrocin ethyl succinate (EXACT_SYNONYM)— chebi
erythromycin 2'-(ethyl butanedioate) (EXACT_SYNONYM)— chebi
erythromycin 2'-(ethyl succinate) (EXACT_SYNONYM)— chebi
erythromycin ethyl succinate (EXACT_SYNONYM)— chebi
erythromycin mono(ethyl succinate) (EXACT_SYNONYM)— chebi
erythromycin, mono(ethyl succinate) (ester) (EXACT_SYNONYM)— chebi
succinic acid, ethyl ester, monoester with erythromycin (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:1264-62-6
drugcentral:1051
kegg.compound:C12796
kegg.drug:D01361
lincs.smallmolecule:LSM-3144
lipidmaps:LMPK05000001
patent:CN1602887
reaxys:77638

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:31555`	erythromycin ethylsuccinate	`antibioticmech:chebi-8b44f71824`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.