erythromycin-[N-methyl-14C]

CHEBI:145339 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A 14C-modified compound that is erythromycin A in which one of the methyl groups of the dimethylnitrilo group has a 14C label. It is used in a breath test to detect liver cytochrome P450 enzyme (CYP3A4) activity in humans. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:139542 CHEBI:139542
CHEBI:3992 CHEBI:3992
CHEBI:48923 CHEBI:48923

Chemical structure

Computed structure properties
Molecular formula	C36[14C]H67NO13
Charge	0
Average mass	735.929 Da
Monoisotopic mass	735.46448 Da
Source	ChEBI
InChIKey	ULGZDMOVFRHVEP-RFAHSBMDSA-N

SMILES

CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)[14CH3])[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

InChI

InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1/i11+2

Also called

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-6-[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-[methyl((114C)methyl)amino]oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione (EXACT_SYNONYM)— chebi
14C-N-methyl-erythromycin (EXACT_SYNONYM)— chebi
[14C-N-methyl]-erythromycin (EXACT_SYNONYM)— chebi
[N-methyl-14C]-erythromycin (EXACT_SYNONYM)— chebi
[N-methyl-14C]erythromycin (EXACT_SYNONYM)— chebi
erythromycin N-methyl C-14 (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:92530-59-1

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:145339`	erythromycin-[N-methyl-14C]	`antibioticmech:chebi-b5a6a21d52`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.