AntibioticMech

macrocin

CHEBI:17371 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A macrolide antibiotic that is tylonolide having mono- and diglycosyl moieties attached to two of its hydroxy groups. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:17478 CHEBI:17478
• CHEBI:25022 CHEBI:25022
• CHEBI:25105 CHEBI:25105
• CHEBI:51689 CHEBI:51689
• CHEBI:63353 CHEBI:63353
• CHEBI:63367 CHEBI:63367

Chemical structure

Computed structure properties

Molecular formula	C45H75NO17
Charge	0
Average mass	902.085 Da
Monoisotopic mass	901.5035 Da
Source	ChEBI
InChIKey	UFUYRGNJTFAODM-HQCAVAADSA-N

SMILES

CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](O)[C@H]1OC

InChI

InChI=1S/C45H75NO17/c1-12-32-29(21-57-44-41(56-11)38(53)36(51)25(5)59-44)17-22(2)13-14-30(48)23(3)18-28(15-16-47)39(24(4)31(49)19-33(50)61-32)63-43-37(52)35(46(9)10)40(26(6)60-43)62-34-20-45(8,55)42(54)27(7)58-34/h13-14,16-17,23-29,31-32,34-44,49,51-55H,12,15,18-21H2,1-11H3/b14-13+,22-17+/t23-,24+,25-,26-,27+,28+,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43+,44-,45-/m1/s1

Also called

• [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-[3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyloxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2-O-methyl-β-D-allopyranoside (EXACT_SYNONYM)— chebi
• 3(sup C)-O-Demethyltylosin (EXACT_SYNONYM)— chebi
• Macrocin (EXACT_SYNONYM)— chebi
• Tylosin C (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:11049-15-3
• kegg.compound:C00744
• knapsack:C00018716
• reaxys:6468979
• wikipedia.en:Macrocin

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:17371	macrocin	antibioticmech:chebi-53c510850b	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.