monacolin J

CHEBI:79034 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A polyketide that is monacolin L bearing an additional hydroxy substituent at position 8. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:142348 CHEBI:142348
CHEBI:26188 CHEBI:26188
CHEBI:35681 CHEBI:35681
CHEBI:36785 CHEBI:36785
CHEBI:75885 CHEBI:75885

Chemical structure

Computed structure properties
Molecular formula	C19H28O4
Charge	0
Average mass	320.429 Da
Monoisotopic mass	320.19876 Da
Source	ChEBI
InChIKey	ZDFOBOYQVYMVCW-IRUSZSJRSA-N

SMILES

[H][C@@]12C(=C[C@H](C)C[C@@H]1O)C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1

InChI

InChI=1S/C19H28O4/c1-11-7-13-4-3-12(2)16(19(13)17(21)8-11)6-5-15-9-14(20)10-18(22)23-15/h3-4,7,11-12,14-17,19-21H,5-6,8-10H2,1-2H3/t11-,12-,14+,15+,16-,17-,19-/m0/s1

Also called

(4R,6R)-4-hydroxy-6-{2-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}tetrahydro-2H-pyran-2-one (EXACT_SYNONYM)— chebi
Antibiotic MB 530A (EXACT_SYNONYM)— chebi
Lovastatin diol lactone (EXACT_SYNONYM)— chebi
Monacolin J (EXACT_SYNONYM)— chebi
monacolin J lactone (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:79952-42-4
knapsack:C00018632
reaxys:4758897
wikipedia.en:Monacolin_J

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:79034`	monacolin J	`antibioticmech:chebi-e98e84d480`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.