O-demethylpuromycin

CHEBI:17161 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A derivative of puromycin lacking the O-methyl group on the tyrosyl residue. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:26404 CHEBI:26404

Chemical structure

Computed structure properties
Molecular formula	C21H27N7O5
Charge	0
Average mass	457.491 Da
Monoisotopic mass	457.20737 Da
Source	ChEBI
InChIKey	NVZJDPXVSWFFJJ-YXDKPKCJSA-N

SMILES

CN(C)c1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)[C@H]1O

InChI

InChI=1S/C21H27N7O5/c1-27(2)18-16-19(24-9-23-18)28(10-25-16)21-17(31)15(14(8-29)33-21)26-20(32)13(22)7-11-3-5-12(30)6-4-11/h3-6,9-10,13-15,17,21,29-31H,7-8,22H2,1-2H3,(H,26,32)/t13-,14+,15+,17+,21+/m0/s1

Also called

3'-deoxy-N,N-dimethyl-3'-(L-tyrosinamido)adenosine (EXACT_SYNONYM)— chebi
O-Demethylpuromycin (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:25605 CHEBI:25605

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:17161`	O-demethylpuromycin	`antibioticmech:chebi-a45d6a3d02`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.