phthalylsulfathiazole

CHEBI:9336 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A sulfonamide incorporating 2-carboxybenzamido and 1,3-thiazol-2-yl moieties that is a broad-spectrum antibiotic indicated in the treatment of dysentery, colitis, gastroenteritis and intestinal surgery. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:35358 CHEBI:35358
CHEBI:35735 CHEBI:35735
CHEBI:38418 CHEBI:38418
CHEBI:87228 CHEBI:87228

Chemical structure

Computed structure properties
Molecular formula	C17H13N3O5S2
Charge	0
Average mass	403.441 Da
Monoisotopic mass	403.02966 Da
Source	ChEBI
InChIKey	PBMSWVPMRUJMPE-UHFFFAOYSA-N

SMILES

O=C(O)c1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1

InChI

InChI=1S/C17H13N3O5S2/c21-15(13-3-1-2-4-14(13)16(22)23)19-11-5-7-12(8-6-11)27(24,25)20-17-18-9-10-26-17/h1-10H,(H,18,20)(H,19,21)(H,22,23)

Also called

ftalilsulfatiazol (INN)— chebi
phtalylsulfathiazol (INN)— chebi
phthalylsulfathiazolum (INN)— chebi
2-({4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}carbamoyl)benzoic acid (EXACT_SYNONYM)— chebi
Phthalylsulfathiazole (EXACT_SYNONYM)— chebi
Sulfathalidine (EXACT_SYNONYM)— chebi
phthalylnorsulfazole (EXACT_SYNONYM)— chebi
phthalylsulfonazole (EXACT_SYNONYM)— chebi
phthalylsulphathiazole (EXACT_SYNONYM)— chebi
sulfaphthalazole (EXACT_SYNONYM)— chebi
sulfathalidine (EXACT_SYNONYM)— chebi
sulphaphthalyl (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:85-73-4
drugcentral:2158
kegg.compound:C07659
kegg.drug:D02440
lincs.smallmolecule:LSM-5730
wikipedia.en:Phthalylsulfathiazole

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:9336`	phthalylsulfathiazole	`antibioticmech:chebi-35a4808d12`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.