propamidine isethionate

CHEBI:87175 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A guanidinium salt obtained by combining propamidine with two molar equivalents of isethionic acid. Used for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:64382 CHEBI:64382
CHEBI:83635 CHEBI:83635

Chemical structure

Computed structure properties
Molecular formula	C17H20N4O2.2C2H6O4S
Charge	0
Average mass	564.639 Da
Monoisotopic mass	564.15599 Da
Source	ChEBI
InChIKey	WSOSYBUSMXEYDO-UHFFFAOYSA-N

SMILES

N=C(N)c1ccc(OCCCOc2ccc(C(=N)N)cc2)cc1.O=S(=O)(O)CCO.O=S(=O)(O)CCO

InChI

InChI=1S/C17H20N4O2.2C2H6O4S/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21;2*3-1-2-7(4,5)6/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21);2*3H,1-2H2,(H,4,5,6)

Also called

Golden eye drops (BRAND_NAME)— chebi
2-hydroxyethane-1-sulfonic acid—4,4'-[propane-1,3-diylbis(oxy)]di(benzene-1-carboximidamide) (2/1) (EXACT_SYNONYM)— chebi
[propane-1,3-diylbis(oxy-4,1-phenylene)]bis(iminomethanaminium) bis(2-hydroxyethane-1-sulfonate) (EXACT_SYNONYM)— chebi
M + B 782 (EXACT_SYNONYM)— chebi
M&B 782 (EXACT_SYNONYM)— chebi
Propamidine diisethionate (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:140-63-6
kegg.drug:D08436
reaxys:8178459
wikipedia.en:Propamidine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:87175`	propamidine isethionate	`antibioticmech:chebi-f94d5c00eb`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.