rhizoxin

CHEBI:72590 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

An macrolide antibiotic isolated from the pathogenic plant fungus Rhizopus microsporus. It also exhibits antitumour and antimitotic activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:25105 CHEBI:25105
CHEBI:32955 CHEBI:32955
CHEBI:46812 CHEBI:46812

Chemical structure

Computed structure properties
Molecular formula	C35H47NO9
Charge	0
Average mass	625.759 Da
Monoisotopic mass	625.32508 Da
Source	ChEBI
InChIKey	OWPCHSCAPHNHAV-QIPOKPRISA-N

SMILES

[H][C@]12CC(=O)O[C@]([H])(C1)[C@H](C)/C=C/[C@@]1([H])O[C@]1(C)[C@@H](O)C[C@@]([H])([C@H](C)[C@@H](OC)/C(C)=C/C=C/C(C)=C/c1coc(C)n1)OC(=O)[C@]1([H])O[C@@]1([H])C2

InChI

InChI=1S/C35H47NO9/c1-19(13-25-18-41-23(5)36-25)9-8-10-21(3)32(40-7)22(4)27-17-29(37)35(6)30(45-35)12-11-20(2)26-14-24(16-31(38)42-26)15-28-33(43-28)34(39)44-27/h8-13,18,20,22,24,26-30,32-33,37H,14-17H2,1-7H3/b9-8+,12-11+,19-13+,21-10+/t20-,22+,24+,26-,27+,28+,29+,30-,32+,33-,35-/m1/s1

Also called

(1S,3S,5R,8S,10S,11R,13R,14E,16R,17R)-10-hydroxy-8-[(2S,3R,4E,6E,8E)-3-methoxy-4,8-dimethyl-9-(2-methyl-1,3-oxazol-4-yl)nona-4,6,8-trien-2-yl]-11,16-dimethyl-4,7,12,18-tetraoxatetracyclo[15.3.1.03,5.011,13]henicos-14-ene-6,19-dione (EXACT_SYNONYM)— chebi
Antibiotic WF-1360 (EXACT_SYNONYM)— chebi
WF-1360 (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:90996-54-6
reaxys:5915392

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:72590`	rhizoxin	`antibioticmech:chebi-3434f13829`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.