sulfamethoxypyridazine

CHEBI:102516 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A sulfonamide consisting of pyridazine having a methoxy substituent at the 6-position and a 4-aminobenzenesulfonamido group at the 3-position. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• Label unavailable CHEBI:35358
• Label unavailable CHEBI:37921
• sulfonamide antibiotic CHEBI:87228

Chemical structure

SMILES

COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1

InChI

InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)

Also called

• sulfamethoxypyridazinum (INN)— chebi
• sulfametoxipiridazina (INN)— chebi
• 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide (EXACT_SYNONYM)— chebi
• 3-(4-Aminobenzenesulfonamido)-6-methoxypyridazine (EXACT_SYNONYM)— chebi
• 3-(p-Aminobenzenesulfamido)-6-methoxypyridazine (EXACT_SYNONYM)— chebi
• 3-Methoxy-6-sulfanylamidopyridazine (EXACT_SYNONYM)— chebi
• 3-Sulfa-6-methoxypyridazine (EXACT_SYNONYM)— chebi
• 3-Sulfanilamide-6-methoxypyridazine (EXACT_SYNONYM)— chebi
• 3-Sulfanilamido-6-methoxypyridazine (EXACT_SYNONYM)— chebi
• 3-p-Aminobenzenesulphonamido-6-methoxypyridazine (EXACT_SYNONYM)— chebi
• 4-Amino-N-(6-methoxy-3-pyridazinyl)-benzenesulfonamide (EXACT_SYNONYM)— chebi
• 6-Methoxy-3-pyridazinylsulfanilamide (EXACT_SYNONYM)— chebi
• 6-Methoxy-3-sulfanilamidopyridazine (EXACT_SYNONYM)— chebi
• 6-Sulfanilamido-3-methoxypyridazine (EXACT_SYNONYM)— chebi
• N1-(6-Methoxy-3-pyridazinyl)sulfanilamide (EXACT_SYNONYM)— chebi
• Solfametossipiridazina (EXACT_SYNONYM)— chebi
• Sulfametoxipiridazine (EXACT_SYNONYM)— chebi
• Sulphamethoxypyridazine (EXACT_SYNONYM)— chebi
• sulfamethoxipyridazine (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

• cas:80-35-3
• gmelin:1443440
• lincs.smallmolecule:LSM-5204
• reaxys:277076

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

• drugcentral:2515
• kegg.drug:D02439

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

• patent:US2712012

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• antimicrobial agent CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Mechanism summary

Mode of action

FOLATE_PATHWAY_INHIBITION microbial target — Assigned from ChEBI role CHEBI:50502 (EC 2.5.1.15 (dihydropteroate synthase) inhibitor). ChEBI asserts the role on the compound. The role names a target specific to the microbe or virus — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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