sulfamethoxypyridazine

CHEBI:102516 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A sulfonamide consisting of pyridazine having a methoxy substituent at the 6-position and a 4-aminobenzenesulfonamido group at the 3-position. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:35358 CHEBI:35358
CHEBI:37921 CHEBI:37921
CHEBI:87228 CHEBI:87228

Chemical structure

Computed structure properties
Molecular formula	C11H12N4O3S
Charge	0
Average mass	280.309 Da
Monoisotopic mass	280.06301 Da
Source	ChEBI
InChIKey	VLYWMPOKSSWJAL-UHFFFAOYSA-N

SMILES

COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1

InChI

InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)

Also called

sulfamethoxypyridazinum (INN)— chebi
sulfametoxipiridazina (INN)— chebi
4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide (EXACT_SYNONYM)— chebi
3-(4-Aminobenzenesulfonamido)-6-methoxypyridazine (EXACT_SYNONYM)— chebi
3-(p-Aminobenzenesulfamido)-6-methoxypyridazine (EXACT_SYNONYM)— chebi
3-Methoxy-6-sulfanylamidopyridazine (EXACT_SYNONYM)— chebi
3-Sulfa-6-methoxypyridazine (EXACT_SYNONYM)— chebi
3-Sulfanilamide-6-methoxypyridazine (EXACT_SYNONYM)— chebi
3-Sulfanilamido-6-methoxypyridazine (EXACT_SYNONYM)— chebi
3-p-Aminobenzenesulphonamido-6-methoxypyridazine (EXACT_SYNONYM)— chebi
4-Amino-N-(6-methoxy-3-pyridazinyl)-benzenesulfonamide (EXACT_SYNONYM)— chebi
6-Methoxy-3-pyridazinylsulfanilamide (EXACT_SYNONYM)— chebi
6-Methoxy-3-sulfanilamidopyridazine (EXACT_SYNONYM)— chebi
6-Sulfanilamido-3-methoxypyridazine (EXACT_SYNONYM)— chebi
N1-(6-Methoxy-3-pyridazinyl)sulfanilamide (EXACT_SYNONYM)— chebi
Solfametossipiridazina (EXACT_SYNONYM)— chebi
Sulfametoxipiridazine (EXACT_SYNONYM)— chebi
Sulphamethoxypyridazine (EXACT_SYNONYM)— chebi
sulfamethoxipyridazine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:80-35-3
drugcentral:2515
gmelin:1443440
kegg.drug:D02439
lincs.smallmolecule:LSM-5204
patent:US2712012
reaxys:277076

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:102516`	sulfamethoxypyridazine	`antibioticmech:chebi-14c04df882`	2026-08-30

Mechanism summary

Mode of action: FOLATE_PATHWAY_INHIBITION microbial target — Assigned from ChEBI role CHEBI:50502 (EC 2.5.1.15 (dihydropteroate synthase) inhibitor). ChEBI asserts the role on the compound. The role names a target specific to the microbe or virus — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.