tosufloxacin tosylate hydrate

CHEBI:32248 ·resolve ·ANTIMICROBIAL_UNSPECIFIED ·EXACT SEEDED

A racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin tosylate hydrate. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:60911 CHEBI:60911

Chemical structure

Computed structure properties
Molecular formula	C19H15F3N4O3.C7H8O3S.H2O
Charge	0
Average mass	594.568 Da
Monoisotopic mass	594.1396 Da
Source	ChEBI
InChIKey	SSULTCPIIYRGFQ-UHFFFAOYSA-N

SMILES

Cc1ccc(S(=O)(=O)O)cc1.NC1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccc(F)cc2F)C1.O

InChI

InChI=1S/C19H15F3N4O3.C7H8O3S.H2O/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25;1-6-2-4-7(5-3-6)11(8,9)10;/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29);2-5H,1H3,(H,8,9,10);1H2

Also called

Ozex (BRAND_NAME)— chebi
rac-1-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]pyrrolidin-3-aminium 4-methylbenzenesulfonate—water (1/1) (EXACT_SYNONYM)— chebi
rac-7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate—water (1/1) (EXACT_SYNONYM)— chebi
(RS)-tosufloxacin tosylate hydrate (EXACT_SYNONYM)— chebi
(±)-tosufloxacin tosylate hydrate (EXACT_SYNONYM)— chebi
Tosufloxacin tosylate monohydrate (EXACT_SYNONYM)— chebi
rac-tosufloxacin tosylate hydrate (EXACT_SYNONYM)— chebi
racemic tosufloxacin tosylate hydrate (EXACT_SYNONYM)— chebi
tosufloxacin monotosylate monohydrate (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:1400591-39-0
kegg.drug:D01996
wikipedia.en:Tosufloxacin

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:32248`	tosufloxacin tosylate hydrate	`antibioticmech:chebi-577c9a83f4`	2026-08-30

Mechanism summary

Mode of action: NUCLEIC_ACID_SYNTHESIS_INHIBITION microbial target — Assigned from ChEBI role CHEBI:53559 (topoisomerase IV inhibitor), CHEBI:59517 (DNA synthesis inhibitor). ChEBI asserts the role on the compound. The role names a target specific to the microbe or virus — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.