BioModels MODEL2407300002 Sponge Holobiont Network

Community ID CommunityMech:000013

Ecological State STABLE

BioModels record MODEL2407300002 provides simulations and model assets for an eight-species sponge microbiome network, modeling interactions among symbiont clades in a Stylissa holobiont.

Taxonomy

Taxon	Ontology ID	Functional Roles	Abundance
Ammonia-oxidizing archaea	NCBITaxon:2157	PRIMARY_PRODUCER	N/A
Nitrite-oxidizing bacteria	NCBITaxon:2	PRIMARY_PRODUCER	N/A
Novel cross-feeding bacterial taxon	NCBITaxon:2	CROSS_FEEDER	N/A

Ecological Interactions

Taxon

Cross-feeding

Mutualism

Syntrophy

Competition

Commensalism

Coupled Nitrification in Stylissa Holobiont

SYNTROPHY

Metabolites: ammonia (CHEBI:16134), nitrite (CHEBI:16301), nitrate (CHEBI:17632)

Biological Processes:

nitrification (GO:0019329)

Evidence

PMID:39738126 - SUPPORT (COMPUTATIONAL)

"Eight genome-scale metabolic models representing seven bacterial and one archaeal species constructed and manually curated based on metagenome-assembled genomes"

Nutrient-Responsive Cross-Feeding Network

CROSS_FEEDING

Evidence

PMID:39738126 - SUPPORT (COMPUTATIONAL)

"the key role that a newly discovered bacterial taxon has in cross-feeding activities"
PMID:39738126 - SUPPORT (COMPUTATIONAL)

"different organic inputs can result in net heterotrophy or autotrophy of the symbiont community"

Sponge-Derived Nutrient Provisioning to Microbiome

MUTUALISM

Evidence

PMID:39738126 - SUPPORT (COMPUTATIONAL)

"Eight genome-scale metabolic models representing seven bacterial and one archaeal species constructed and manually curated based on metagenome-assembled genomes"

Associated Datasets

Dataset	Type	Repository	Accession
Primary publication Nature Communications article describing genome-scale metabolic modeling of Stylissa holobiont microbiome.	OTHER	OTHER	doi:10.1038/s41467-024-55222-w
BioModels simulation resource RDS simulation object for eight-species metabolic network.	OTHER	OTHER	8-species_network_simulations_HT_and_Laurate_100th_hr.RDS