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Defined Multispecies Enamel Caries Model

Community ID CommunityMech:000082
Ecological State ENGINEERED
Environment cariogenic enamel biofilm on tooth surface
ENVO:01001034

A defined four-member oral biofilm model for in vitro enamel caries development, composed of Lactobacillus casei, Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguinis on salivary-pellicle-coated enamel slabs. The system was used to quantify how sucrose, fluoride, and calcium shift biofilm growth and enamel demineralization.

Taxonomy

Taxon Ontology ID Functional Roles Abundance
Lactobacillus casei NCBITaxon:1582 N/A
  • PMID:23446436 - SUPPORT (IN_VITRO)
    "Defined-multispecies biofilms, formed by Lactobacillus casei, Streptococcus mutans, S. salivarius and S. sanguinis, were grown on the surface of salivary-pellicle-coated enamel slabs"
Streptococcus mutans NCBITaxon:1309 N/A
  • PMID:23446436 - SUPPORT (IN_VITRO)
    "Defined-multispecies biofilms, formed by Lactobacillus casei, Streptococcus mutans, S. salivarius and S. sanguinis, were grown on the surface of salivary-pellicle-coated enamel slabs"
Streptococcus salivarius NCBITaxon:1304 N/A
  • PMID:23446436 - SUPPORT (IN_VITRO)
    "Defined-multispecies biofilms, formed by Lactobacillus casei, Streptococcus mutans, S. salivarius and S. sanguinis, were grown on the surface of salivary-pellicle-coated enamel slabs"
Streptococcus sanguinis NCBITaxon:1305 N/A
  • PMID:23446436 - SUPPORT (IN_VITRO)
    "Defined-multispecies biofilms, formed by Lactobacillus casei, Streptococcus mutans, S. salivarius and S. sanguinis, were grown on the surface of salivary-pellicle-coated enamel slabs"

Ecological Interactions

ℹ️ No detailed ecological interaction data is available for this community.

This record may be a metabolic model or minimal entry containing only taxonomy and external resource links.

Environmental Factors

Factor Value Unit
Sucrose concentration 0.5-1.0 %
  • PMID:23446436 - SUPPORT (IN_VITRO)
    "The aims of this study were to describe and validate an in vitro multispecies microbial biofilm model for caries development by evaluating the effects of varying medium concentration of sucrose (0.5 and 1.0%)"
Fluoride concentration 0.4-1.0 ppm
  • PMID:23446436 - SUPPORT (IN_VITRO)
    "There was a decrease in %SMC in response to increased fluoride and calcium concentrations (p < 0.001). Lower IML (p < 0.001) and LD (p < 0.05) were found in the presence of 0.8 and 1.0 ppm F."
Calcium concentration 1.0-2.0 mM
  • PMID:23446436 - SUPPORT (IN_VITRO)
    "There was a decrease in %SMC in response to increased fluoride and calcium concentrations (p < 0.001)."