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Syntrophomonas-Methanococcus Butyrate Growth Coordination Coculture

A defined mesophilic anaerobic coculture pairing the butyrate-oxidizing syntroph Syntrophomonas wolfei with the hydrogenotrophic methanogen Methanococcus maripaludis. The system is used to study how a fatty acid-oxidizing bacterium and a methanogen synchronize growth, form syntrophic aggregates, and maintain cell-to-cell attraction during methanogenic butyrate conversion. It is relevant to DOE interests in anaerobic carbon cycling, methane production, syntrophic energy sharing, and engineered bioreactor microbiology.

Taxonomy

Taxon Ontology ID Functional Roles Abundance
Syntrophomonas wolfei NCBITaxon:863
PRIMARY_DEGRADER SYNTROPHIC_PARTNER
N/A
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "mesophilic coculture consisting of Syntrophomonas wolfei and Methanococcus maripaludis"
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "butyrate-oxidizing bacteria and methanogens"
Methanococcus maripaludis NCBITaxon:39152
SYNTROPHIC_PARTNER CROSS_FEEDER
N/A
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "mesophilic coculture consisting of Syntrophomonas wolfei and Methanococcus maripaludis"
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "hydrogenotrophic methanogens"

Ecological Interactions

Ecological interaction network for Syntrophomonas-Methanococcus Butyrate Growth Coordination Coculture Bipartite graph where circle nodes represent taxa and colored rectangles represent ecological interactions (cross-feeding, mutualism, syntrophy, competition, commensalism).
Taxon
Cross-feeding
Mutualism
Syntrophy
Competition
Commensalism
Niche partitioning
Colonization facilitation
Strain competition
Predation

Syntrophic Butyrate Oxidation and Methanogenesis

SYNTROPHY

Source Taxon: Syntrophomonas wolfei

Target Taxon: Methanococcus maripaludis

Metabolites: butyrate (CHEBI:17968), methane (CHEBI:16183)

Biological Processes:

Evidence

  • PMID:34603271 - SUPPORT (IN_VITRO)
    "thermodynamically required mutualistic cooperation between fatty acid-oxidizing bacteria and methanogens"
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "butyrate-oxidizing bacteria and methanogens"

Population Ratio Convergence During Growth

MUTUALISM

Source Taxon: Syntrophomonas wolfei

Target Taxon: Methanococcus maripaludis

Biological Processes:

  • interspecies interaction between organisms (GO:0044419)

Evidence

  • PMID:34603271 - SUPPORT (IN_VITRO)
    "syntrophs and methanogens were inoculated at different initial cell ratios"
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "the cell ratio converged over time to relative constant values"

Syntrophic Aggregation and Cell-to-Cell Attraction

COLONIZATION_FACILITATION

Source Taxon: Syntrophomonas wolfei

Target Taxon: Methanococcus maripaludis

Biological Processes:

  • interspecies interaction between organisms (GO:0044419)

Evidence

  • PMID:34603271 - SUPPORT (IN_VITRO)
    "tendency of syntrophic aggregation was not affected by the physical disturbances"
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "suggesting the cell-to-cell attraction between Syntrophomonas and Methanococcus"

External Resources

Name Repository Resource ID
Exact-system primary publication - S. wolfei and M. maripaludis growth coordination
Primary publication reporting growth synchronization, aggregation, and cell-to-cell attraction in the S. wolfei and M. maripaludis coculture.
OTHER PMID:34603271
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "mesophilic coculture consisting of Syntrophomonas wolfei and Methanococcus maripaludis"
Exact-system publication - conductive nanomaterial stimulation
Additional exact-composition publication reporting a defined S. wolfei and M. maripaludis coculture used to test carbon nanotubes and reduced graphene oxide during syntrophic butyrate oxidation.
OTHER doi:10.1038/s41598-018-30745-7
DOI landing page - growth coordination publication
DOI landing page for the growth coordination publication.
OTHER doi:10.3389/fmicb.2021.742531
NCBI Taxonomy - Syntrophomonas wolfei
NCBI Taxonomy record for Syntrophomonas wolfei.
OTHER NCBITaxon:863
NCBI Taxonomy - Methanococcus maripaludis
NCBI Taxonomy record for Methanococcus maripaludis.
OTHER NCBITaxon:39152

Environmental Factors

Factor Value Unit
Anoxic methanogenic context anoxic environments N/A
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "organic decomposition and methanogenesis in anoxic environments"
Initial partner ratio variable syntroph-to-methanogen starting ratios N/A
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "inoculated at different initial cell ratios to evaluate the growth synchronization"
Physical disturbance intermittent ultrasound and constant shaking N/A
  • PMID:34603271 - SUPPORT (IN_VITRO)
    "intermittent ultrasound and constant shaking treatments"

Growth Media