DUFMech

All families / PF01174

PF01174: SNO

SNO glutamine amidotransferase family

Curation status
SEEDED
Seed status
EX DUF
Characterization
UNSCORED

Grounding

PF01174: SNO glutamine amidotransferase family
IPR002161: integrated entry for SNO glutamine amidotransferase family

Source description

This family and its amidotransferase domain was first described in [InterPro reference PUB00020352]. It is predicted that members of this family are involved in the pyridoxine biosynthetic pathway, based on the proximity and co-regulation of the corresponding genes and physical interaction between the members of PF01174 (SNO glutamine amidotransferase family) and PF01680 (SOR/SNZ family) [InterPro reference PUB00007176].

Evidence and references

Source descriptions and links are provenance, not independent functional validation.

Evidence counts: not scored.

Curated functional assertions

No curated functional assertions supplied.

Protein sequence examples

7 verified sequence examples. FASTA

UniProtProtein / organismSequenceProvenance
P37528Pyridoxal 5'-phosphate synthase subunit PdxT
Bacillus subtilis (strain 168)
196 aa; version 1
UniProt 2026_03
PTM REGISTRY MIRROR
13 sibling references
P43544Probable pyridoxal 5'-phosphate synthase subunit SNO3
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
222 aa; version 1
UniProt 2026_03
PTM REGISTRY MIRROR
9 sibling references
P53823Probable pyridoxal 5'-phosphate synthase subunit SNO2
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
222 aa; version 1
UniProt 2026_03
UNIPROT FETCH
6 sibling references
Q03144Pyridoxal 5'-phosphate synthase subunit SNO1
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
224 aa; version 1
UniProt 2026_03
UNIPROT FETCH
12 sibling references
Q59055Pyridoxal 5'-phosphate synthase subunit PdxT
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
186 aa; version 1
UniProt 2026_03
UNIPROT FETCH
11 sibling references
Q8IIK4Pyridoxal 5'-phosphate synthase subunit PDX2
Plasmodium falciparum (isolate 3D7)
219 aa; version 2
UniProt 2026_03
UNIPROT FETCH
9 sibling references
Q8LAD0Probable pyridoxal 5'-phosphate synthase subunit PDX2
Arabidopsis thaliana
255 aa; version 1
UniProt 2026_03
UNIPROT FETCH
9 sibling references

Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.

Sequences and metadata: UniProt Consortium, CC BY 4.0.

Domain matches

No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.

Snapshot counters

proteins
9,115
matches
9,939
proteomes
8,607
taxa
14,067
structures
12
alphafold models
6,364
domain architectures
34

Classification basis

pfam previous unknown name

No scoring reasons supplied.

Related Mech records

This family joined the worklist after the frozen cross-Mech scan, so other Mechs were not searched for it. Missing links here are not evidence that other Mechs lack it; rows shown come from mentions of a former DUF/UPF name.

No cross-Mech examples are present in the supplied snapshot.

Curation history and reviews

No retained curation events supplied.

No retained review supplied.

Record source

data/families/PF01174.yaml
Family YAML in this build

Download this family (JSON)

Status and evidence

Seed status
A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
Characterization
A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
Evidence counts
Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
Curation status
Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
Missing counts
Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.