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All families / PF06429

PF06429: Flg_bbr_C

Flagellar basal body rod FlgEFG protein C-terminal

Curation status
SEEDED
Seed status
EX DUF
Characterization
UNSCORED

Grounding

PF06429: Flagellar basal body rod FlgEFG protein C-terminal
IPR010930: integrated entry for Flagellar basal body rod FlgEFG protein C-terminal

Source description

This family consists of a number of C-terminal domains of unknown function. This domain seems to be specific to flagellar basal-body rod and flagellar hook proteins in which PF00460 (Pfam entry) is often present at the extreme N terminus.

Evidence and references

Source descriptions and links are provenance, not independent functional validation.

Evidence counts: not scored.

Curated functional assertions

No curated functional assertions supplied.

Protein sequence examples

18 verified sequence examples. FASTA

UniProtProtein / organismSequenceProvenance
O07884Flagellar hook protein FlgE
Treponema pallidum (strain DSM 117211 / Nichols)
463 aa; version 1
UniProt 2026_03
UNIPROT FETCH
1 sibling references
P0A1I7Flagellar basal-body rod protein FlgC
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
134 aa; version 1
UniProt 2026_03
UNIPROT FETCH
2 sibling references
P0A1J1Flagellar hook protein FlgE
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
403 aa; version 2
UniProt 2026_03
UNIPROT FETCH
2 sibling references
P0A1J3Flagellar basal-body rod protein FlgG
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
260 aa; version 1
UniProt 2026_03
UNIPROT FETCH
2 sibling references
P0A1J5Flagellar hook-associated protein 1
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
553 aa; version 2
UniProt 2026_03
UNIPROT FETCH
3 sibling references
P0ABX2Flagellar basal-body rod protein FlgC
Escherichia coli (strain K12)
134 aa; version 1
UniProt 2026_03
UNIPROT FETCH
5 sibling references
P0ABX5Flagellar basal-body rod protein FlgG
Escherichia coli (strain K12)
260 aa; version 1
UniProt 2026_03
PTM REGISTRY MIRROR
13 sibling references
P16323Flagellar basal-body rod protein FlgF
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
251 aa; version 1
UniProt 2026_03
UNIPROT FETCH
2 sibling references
P23446Flagellar basal-body rod protein FlgG
Bacillus subtilis (strain 168)
264 aa; version 2
UniProt 2026_03
PTM REGISTRY MIRROR
16 sibling references
P24501Flagellar basal-body rod protein FlgC
Bacillus subtilis (strain 168)
150 aa; version 1
UniProt 2026_03
UNIPROT FETCH
6 sibling references

First 10 shown; the FASTA and family JSON contain all examples.

Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.

Sequences and metadata: UniProt Consortium, CC BY 4.0.

Domain matches

No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.

Snapshot counters

proteins
48,344
matches
48,359
proteomes
8,805
taxa
12,724
structures
48
alphafold models
31,623
domain architectures
74

Classification basis

description says unknown function; pfam previous unknown name

No scoring reasons supplied.

Related Mech records

This family joined the worklist after the frozen cross-Mech scan, so other Mechs were not searched for it. Missing links here are not evidence that other Mechs lack it; rows shown come from mentions of a former DUF/UPF name.

No cross-Mech examples are present in the supplied snapshot.

Curation history and reviews

No retained curation events supplied.

No retained review supplied.

Record source

data/families/PF06429.yaml
Family YAML in this build

Download this family (JSON)

Status and evidence

Seed status
A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
Characterization
A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
Evidence counts
Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
Curation status
Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
Missing counts
Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.