DUFMech

All families / PF07004

PF07004: SHIPPO-rpt

Sperm-tail PG-rich repeat

Curation status
SEEDED
Seed status
EX DUF
Characterization
UNSCORED

Grounding

PF07004: Sperm-tail PG-rich repeat
IPR010736: integrated entry for Sperm-tail PG-rich repeat

Source description

This family represents a short conserved region carrying a PGP motif that is repeated in eukaryotic proteins of sperm-tails. Shippo orthologues from some species may include up to 40 Pro-Gly-Pro repeats.

Evidence and references

Source descriptions and links are provenance, not independent functional validation.

Evidence counts: not scored.

Curated functional assertions

No curated functional assertions supplied.

Protein sequence examples

9 verified sequence examples. FASTA

UniProtProtein / organismSequenceProvenance
Q3SX64Protein CIMAP1D
Homo sapiens		289 aa; version 2
UniProt 2026_03		UNIPROT FETCH
1 sibling references
Q5TH74O(6)-methylguanine-induced apoptosis 2
Homo sapiens		334 aa; version 1
UniProt 2026_03		PTM REGISTRY MIRROR
4 sibling references
Q8N801Protein STPG4
Homo sapiens		248 aa; version 2
UniProt 2026_03		UNIPROT FETCH
2 sibling references
Q8TCI5Ciliary microtubule-associated protein 3
Homo sapiens		191 aa; version 2
UniProt 2026_03		PTM REGISTRY MIRROR
4 sibling references
Q920N1Ciliary microtubule associated protein 1A
Mus musculus		254 aa; version 2
UniProt 2026_03		UNIPROT FETCH
1 sibling references
Q96PU9Ciliary microtubule associated protein 1A
Homo sapiens		254 aa; version 1
UniProt 2026_03		UNIPROT FETCH
1 sibling references
Q9D2F5O(6)-methylguanine-induced apoptosis 2
Mus musculus		341 aa; version 1
UniProt 2026_03		UNIPROT FETCH
2 sibling references
Q9D9W1Ciliary microtubule-associated protein 3
Mus musculus		207 aa; version 1
UniProt 2026_03		UNIPROT FETCH
3 sibling references
Q9DAG5Protein STPG4
Mus musculus		247 aa; version 1
UniProt 2026_03		UNIPROT FETCH
3 sibling references

Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.

Sequences and metadata: UniProt Consortium, CC BY 4.0.

Domain matches

No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.

Snapshot counters

proteins
9,242
matches
45,358
proteomes
1,349
taxa
4,508
structures
13
alphafold models
7,665
domain architectures
245

Classification basis

pfam previous unknown name

No scoring reasons supplied.

Related Mech records

This family joined the worklist after the frozen cross-Mech scan, so other Mechs were not searched for it. Missing links here are not evidence that other Mechs lack it; rows shown come from mentions of a former DUF/UPF name.

No cross-Mech examples are present in the supplied snapshot.

Curation history and reviews

No retained curation events supplied.

No retained review supplied.

Record source

data/families/PF07004.yaml
Family YAML in this build

Download this family (JSON)

Status and evidence

Seed status
A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
Characterization
A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
Evidence counts
Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
Curation status
Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
Missing counts
Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.