All families / PF10950
PF10950: Organ_specific
Organ specific protein
- Curation status
- SEEDED
- Seed status
- EX DUF
- Characterization
- UNSCORED
Grounding
PF10950: Organ specific protein
IPR024489: integrated entry for Organ specific protein
Source description
This eukaryotic family includes a number of plant organ-specific proteins. The predicted amino acid sequence suggests that these proteins could be exported and glycosylated [InterPro reference PUB00056161]. Family members consist of an N-terminal region with no repeats and a C-terminal region which carries multiple tandem repeats. The N-terminal region ends before the repeats region and is defined as the area that extends from the end of the signal peptide to the start of the tandem repeat region. Its length varies considerably, ranging from 30 to 80 amino acids. Generally, these proteins vary in size where it is suggested that thirty-six percent of the sequences had fewer than 150 amino acids; 41% ranged from 150 to 250, and 23% had more than 250 amino acids. Accordingly, these proteins belong to category II of proteins having repeats in tandem; that is, those with the repeats ranging in length from 20 to 40 residues. The second region (C-terminal) in the mature protein is the tandem repeat oligopeptide area. The repeats start with a common hexapeptide (E/D)FEPRP and end with X4Y i .e. (D/E)FEPRPX4Y. Full-length sequences revealed considerable variability in the number of repeats, ranging from 2 to 17. The length of the repeats also varied, ranging from 12 amino acids to 34 amino acids [InterPro reference PUB00109583].
Evidence and references
- InterPro entry and its literature references. PUB identifiers are internal InterPro references, not PubMed identifiers. Unresolved citations link to the originating entry.
- Frozen description source: InterPro/Pfam API
Source descriptions and links are provenance, not independent functional validation.
Evidence counts: not scored.
Curated functional assertions
No curated functional assertions supplied.
Protein sequence examples
No sibling protein candidate in the scanned commits.
Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.
Sequences and metadata: UniProt Consortium, CC BY 4.0.
Domain matches
No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.
Snapshot counters
- proteins
- 1,279
- matches
- 1,970
- proteomes
- 250
- taxa
- 663
- structures
- 0
- alphafold models
- 939
- domain architectures
- 20
Classification basis
pfam previous unknown name
No scoring reasons supplied.
Related Mech records
This family joined the worklist after the frozen cross-Mech scan, so other Mechs were not searched for it. Missing links here are not evidence that other Mechs lack it; rows shown come from mentions of a former DUF/UPF name.
No cross-Mech examples are present in the supplied snapshot.
Curation history and reviews
No retained curation events supplied.
No retained review supplied.
Record source
Status and evidence
- Seed status
- A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
- Characterization
- A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
- Evidence counts
- Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
- Curation status
- Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
- Missing counts
- Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.