DUFMech

All families / PF19906

PF19906: CGDB

C-glycoside deglycosidase beta subunit

Curation status
SEEDED
Seed status
EX DUF
Characterization
UNSCORED

Grounding

PF19906: C-glycoside deglycosidase beta subunit
IPR045959: integrated entry for C-glycoside deglycosidase beta subunit

Source description

This is the structural domain of C-glycoside deglycosidase beta subunit (CGDB, also known as CarC), a carbon-carbon bond-cleaving enzyme which participates in the metabolism of C-glycosides [InterPro reference PUB00155029]. It acts on the C6-glycosylated compounds 3''-dehydroisovitexin (3''-oxo-isovitexin) and 3''-dehydroisoorientin (3''-oxo-homoorientin) [InterPro reference PUB00155029]. In some members, this domain is found in combination with other domains.

Evidence and references

Source descriptions and links are provenance, not independent functional validation.

Evidence counts: not scored.

Curated functional assertions

No curated functional assertions supplied.

Protein sequence examples

3 verified sequence examples. FASTA

UniProtProtein / organismSequenceProvenance
H0QPM1C-glycoside deglycosidase beta subunit
Arthrobacter globiformis (strain ATCC 8010 / DSM 20124 / JCM 1332 / NBRC 12137 / NCIMB 8907 / NRRL B-2979 / 168)
131 aa; version 1
UniProt 2026_03
UNIPROT FETCH
1 sibling references
I5AX49C-glycoside deglycosidase beta subunit
Eubacterium cellulosolvens (strain ATCC 43171 / JCM 9499 / 6)
147 aa; version 1
UniProt 2026_03
UNIPROT FETCH
1 sibling references
P0DXE63'-dehydrocarminate deglycosidase beta subunit
Microbacterium sp
132 aa; version 1
UniProt 2026_03
UNIPROT FETCH
1 sibling references

Pfam membership is not functional evidence. Whole-protein sequences do not establish domain boundaries. A coverage gap here is not absence from UniProt.

Sequences and metadata: UniProt Consortium, CC BY 4.0.

Domain matches

No residue-level domain match evidence is available in this build. Structure and AlphaFold counters do not supply coordinates or establish function.

Snapshot counters

proteins
826
matches
826
proteomes
350
taxa
648
structures
16
alphafold models
496
domain architectures
3

Classification basis

pfam previous unknown name

No scoring reasons supplied.

Related Mech records

This family joined the worklist after the frozen cross-Mech scan, so other Mechs were not searched for it. Missing links here are not evidence that other Mechs lack it; rows shown come from mentions of a former DUF/UPF name.

No cross-Mech examples are present in the supplied snapshot.

Curation history and reviews

No retained curation events supplied.

No retained review supplied.

Record source

data/families/PF19906.yaml
Family YAML in this build

Download this family (JSON)

Status and evidence

Seed status
A name-based classification of frozen InterPro/Pfam metadata. UNKNOWN CANDIDATE means the metadata explicitly says the function is unknown. KNOWN HISTORICAL DUF means a DUF name matched without that wording; this heuristic is not proof of a known function and does not establish experimental characterization. EX DUF means Pfam renamed the family away from a DUF/UPF name, as recorded in Pfam's previous identifiers; a rename usually follows published work on some members but is naming history, not proof of function for every member. Some EX DUF families' current names or descriptions still say the function is unknown; their classification basis lists this, and scoring does not treat them as characterized. FALSE POSITIVE TEXT HIT means the naming rules did not match.
Characterization
A separate evidence-scoring result. UNSCORED means no score has been calculated; it is not evidence that the family lacks a known function. Missing scores are not negative evidence. PARTIALLY CHARACTERIZED has partial support; KNOWN HISTORICAL DUF can inherit the seed label or reflect a known-function signal. Neither label implies experimental validation.
Evidence counts
Source-specific signals, not unique proteins, publications, or confidence scores. Known counts Rhea reactions and experimentally supported GO molecular-function annotations. Partial counts functional/domain assignments. Context counts structural, environmental, orthology, interaction and neighborhood signals; context alone does not assign function. Repeated annotations may not be independent.
Curation status
Reported separately from seed classification and characterization. SNAPSHOT ONLY means no curated metadata was supplied for this build. SEEDED denotes a source-derived record, not an expert-reviewed functional claim.
Missing counts
Not available means the source did not supply that counter. A zero is a reported count. Not scored means evidence counts are unavailable.