NaturalProductMech

12-epi-fischerindole I isonitrile

naturalproductmech:mibig-bc49771bdc MINTED SEEDED

Structure

Standard InChIKeyZVBCZYGMKQOJFW-QDUSTFBWSA-N
SMILESCC1(C)[C@H]2C[C@@H](Cl)[C@@](C)(C=C)C([N+]#[C-])=C2C2=C1NC1=CC=CC=C21
Stereochemistryfully defined
Cross-referencescyanometdb:CyanoMetDB_1565, npatlas:NPA04901

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Hapalosiphon welwitschii UTEX B 1830
NCBITaxon:1433842
SOURCE_ASSERTION mibig:BGC0000668 DOI:10.1021/ja00101a015

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Hapalosiphon welwitschii
NCBITaxon:162986
LOTUS DOI:10.1021/JA00101A015
Hapalosiphon welwitschii
NCBITaxon:162986
LOTUS DOI:10.1021/JA00166A066
Hapalosiphon welwitschii
NCBITaxon:162986
CYANOMETDB DOI:10.1021/ja00101a015

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000668 Hapalosiphon welwitschii UTEX B 1830
NCBITaxon:1433842
CLUSTER_DEMONSTRATED genbank:KF811479.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000668MIBIG5

This page is generated from data/natural_products/alkaloids/12-epi-fischerindole-i-isonitrile.yaml, which is generated from the committed inventories. Neither is edited by hand.