NaturalProductMech

12-epi-hapalindole C isonitrile

naturalproductmech:mibig-4505b19edb MINTED SEEDED

Structure

Standard InChIKeyKGWATBYKCMCFLC-CGRMTHRGSA-N
SMILESCC(=C)[C@H]1CC[C@@]([C@@H]([C@@H]1C2=CNC3=CC=CC=C32)[N+]#[C-])(C)C=C
Stereochemistryfully defined
Cross-referencesnpatlas:NPA016387, cyanometdb:CyanoMetDB_1547

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Hapalosiphon welwitschii UTEX B 1830
NCBITaxon:1433842
SOURCE_ASSERTION mibig:BGC0000668 DOI:10.1021/jo00226a009

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fischerella
NCBITaxon:1190
LOTUS DOI:10.1016/J.PHYTOCHEM.2007.06.024
Fischerella
NCBITaxon:1190
LOTUS DOI:10.1021/JA00101A015
Hapalosiphon
NCBITaxon:162985
LOTUS DOI:10.1021/NP50125A025
Hapalosiphon welwitschii
NCBITaxon:162986
LOTUS DOI:10.1002/CBIC.201300794
Hapalosiphon welwitschii
NCBITaxon:162986
LOTUS DOI:10.1016/J.PHYTOCHEM.2007.06.024
Hapalosiphon welwitschii
NCBITaxon:162986
LOTUS DOI:10.1021/JO00226A009

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000668 Hapalosiphon welwitschii UTEX B 1830
NCBITaxon:1433842
CLUSTER_DEMONSTRATED genbank:KF811479.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000668MIBIG5

This page is generated from data/natural_products/alkaloids/12-epi-hapalindole-c-isonitrile.yaml, which is generated from the committed inventories. Neither is edited by hand.