12-epi-hapalindole E

naturalproductmech:mibig-fa36d6dbf9 MINTED SEEDED

Structure

Standard InChIKey	IJEJDCXOVNHHAX-CMWLGVBASA-N
SMILES	CC(=C)[C@H]1C[C@@H](Cl)[C@@](C)(C=C)[C@H]([N+]#[C-])[C@@H]1C1=CNC2=C1C=CC=C2
Stereochemistry	fully defined
Cross-references	npatlas:NPA015996, cyanometdb:CyanoMetDB_1553

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Hapalosiphon welwitschii UTEX B 1830 NCBITaxon:1433842	SOURCE_ASSERTION	mibig:BGC0000668	DOI:10.1021/jo00226a009

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Fischerella NCBITaxon:1190	LOTUS	DOI:10.1016/J.PHYTOCHEM.2007.06.024
Hapalosiphon NCBITaxon:162985	LOTUS	DOI:10.1016/J.PHYTOCHEM.2007.06.024
Hapalosiphon NCBITaxon:162985	LOTUS	DOI:10.1021/NP50125A025
Hapalosiphon welwitschii NCBITaxon:162986	CYANOMETDB	DOI:10.1002/cbic.201300794
Hapalosiphon welwitschii NCBITaxon:162986	LOTUS	DOI:10.1021/JO00226A009

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0000668	Hapalosiphon welwitschii UTEX B 1830 NCBITaxon:1433842	CLUSTER_DEMONSTRATED	genbank:KF811479.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source concept	Source	Version
BGC0000668	MIBIG	5

This page is generated from data/natural_products/alkaloids/12-epi-hapalindole-e.yaml, which is generated from the committed inventories. Neither is edited by hand.