17-hydroxy-8-desmethoxy-isomigrastatin
naturalproductmech:mibig-c995bb8923 MINTED SEEDED
Structure
| Standard InChIKey | IVFXTQLBVDABOI-DVYWRAFASA-N |
|---|---|
| SMILES | C[C@@H](\C=C(/C)[C@@H]1OC(=O)\C=C\CC\C=C\C[C@@H](O)[C@@H]1C)C(=O)C[C@H](O)CC1CC(=O)NC(=O)C1 |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA013831 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces amphibiosporus NCBITaxon:221586 |
BGC_CHARACTERIZED | mibig:BGC0000083 | PMID:25405956 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces platensis NCBITaxon:58346 |
LOTUS | DOI:10.1021/JA053118U |
| Streptomyces amphibiosporus NCBITaxon:221586 |
LOTUS | DOI:10.1021/OL702249G |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000083 | Streptomyces amphibiosporus NCBITaxon:221586 |
CLUSTER_DEMONSTRATED | genbank:GQ274954.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000083 | MIBIG | 5 |
This page is generated from data/natural_products/alkaloids/17-hydroxy-8-desmethoxy-isomigrastatin.yaml, which is generated from the committed inventories. Neither is edited by hand.