2-heptylquinolin-4(1H)-one
naturalproductmech:mibig-182e475a70 REVIEW_NEEDED SEEDED antibacterial
Structure
| Standard InChIKey | UYRHHBXYXSYGHA-UHFFFAOYSA-N |
|---|---|
| SMILES | CCCCCCCC1=CC(=O)C2=CC=CC=C2N1 |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA026460 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Pseudomonas aeruginosa PAO1 NCBITaxon:208964 |
SOURCE_ASSERTION | mibig:BGC0000922 | DOI:10.1016/j.chembiol.2013.09.021 |
Occurrences 7
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Haplophyllum griffithianum NCBITaxon:1006075 |
LOTUS | DOI:10.1007/S10600-010-9661-Y |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.3390/MD17020133 |
| Pseudomonas aeruginosa NCBITaxon:287 |
LOTUS | DOI:10.1016/S0021-9258(17)41580-8 |
| Pseudomonas aeruginosa NCBITaxon:287 |
LOTUS | DOI:10.1016/S0040-4039(01)83977-0 |
| Ruta graveolens NCBITaxon:37565 |
LOTUS | DOI:10.1007/PL00010251 |
| Ruta graveolens NCBITaxon:37565 |
LOTUS | DOI:10.1007/S007060050230 |
| Pseudoalteromonas NCBITaxon:53246 |
LOTUS | DOI:10.3390/MD15110336 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000922 | Pseudomonas aeruginosa PAO1 NCBITaxon:208964 |
CLUSTER_UNSTATED | genbank:AE004091.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:62219 (same structure, same inchikey)
- AntibioticMech — CHEBI:75306 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000922 | MIBIG | 5 |
| CHEBI:62219 | CHEBI | 3-star |
| CHEBI:75306 | CHEBI | 3-star |
This page is generated from data/natural_products/alkaloids/2-heptylquinolin-4-1h-one.yaml, which is generated from the committed inventories. Neither is edited by hand.