ambiguine A isonitrile
naturalproductmech:mibig-a033f9fea7 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | GHYIJWADNLIVDB-UMIISBCRSA-N |
|---|---|
| SMILES | C[C@@]1([C@@H](C[C@H]2[C@H]([C@H]1[N+]#[C-])C3=C(NC4=CC=CC(=C43)C2(C)C)C(C)(C)C=C)Cl)C=C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:21610112 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Fischerella ambigua UTEX 1903 NCBITaxon:230521 |
SOURCE_ASSERTION | mibig:BGC0001126 | PMID:24180436 |
Occurrences 6
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Fischerella NCBITaxon:1190 |
LOTUS | DOI:10.1021/NP060495R |
| Fischerella NCBITaxon:1190 |
LOTUS | DOI:10.1021/NP060495R.S001 |
| Hapalosiphon delicatulus NCBITaxon:210996 |
LOTUS | DOI:10.1021/NP9801561 |
| Fischerella ambigua NCBITaxon:56108 |
LOTUS | DOI:10.1021/JO00029A014 |
| Fischerella ambigua NCBITaxon:56108 |
LOTUS | DOI:10.1021/NP800751J |
| Fischerella ambigua NCBITaxon:56108 |
CYANOMETDB | DOI:10.1021/jo00029a014 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001126 | Fischerella ambigua UTEX 1903 NCBITaxon:230521 |
CLUSTER_DEMONSTRATED | genbank:KF664586.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001126 | MIBIG | 4 |
This page is generated from data/natural_products/alkaloids/ambiguine-a-isonitrile.yaml, which is generated from the committed inventories. Neither is edited by hand.