NaturalProductMech

ambiguine A isonitrile

naturalproductmech:mibig-a033f9fea7 MINTED SEEDED

Structure

Standard InChIKeyGHYIJWADNLIVDB-UMIISBCRSA-N
SMILESC[C@@]1([C@@H](C[C@H]2[C@H]([C@H]1[N+]#[C-])C3=C(NC4=CC=CC(=C43)C2(C)C)C(C)(C)C=C)Cl)C=C
Stereochemistryfully defined
Cross-referencespubchem:21610112

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Fischerella ambigua UTEX 1903
NCBITaxon:230521
SOURCE_ASSERTION mibig:BGC0001126 PMID:24180436

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fischerella
NCBITaxon:1190
LOTUS DOI:10.1021/NP060495R
Fischerella
NCBITaxon:1190
LOTUS DOI:10.1021/NP060495R.S001
Hapalosiphon delicatulus
NCBITaxon:210996
LOTUS DOI:10.1021/NP9801561
Fischerella ambigua
NCBITaxon:56108
LOTUS DOI:10.1021/JO00029A014
Fischerella ambigua
NCBITaxon:56108
LOTUS DOI:10.1021/NP800751J
Fischerella ambigua
NCBITaxon:56108
CYANOMETDB DOI:10.1021/jo00029a014

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001126 Fischerella ambigua UTEX 1903
NCBITaxon:230521
CLUSTER_DEMONSTRATED genbank:KF664586.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001126MIBIG4

This page is generated from data/natural_products/alkaloids/ambiguine-a-isonitrile.yaml, which is generated from the committed inventories. Neither is edited by hand.