NaturalProductMech

ambiguine K isonitrile

naturalproductmech:mibig-801a93942c MINTED SEEDED

Structure

Standard InChIKeyRSUTYZFOFIAHFY-OWINPNOJSA-N
SMILESCC1(C)[C@H]2C[C@@H](Cl)[C@](C)(C=C)[C@]3(C=CC(C)(C)C4=C(C5=C1C=CC=C5N4)[C@]23O)[N+]#[C-]
Stereochemistryfully defined
Cross-referencesnpatlas:NPA01055, pubchem:44139368

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Fischerella ambigua UTEX 1903
NCBITaxon:230521
SOURCE_ASSERTION mibig:BGC0001126 PMID:24180436

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fischerella ambigua
NCBITaxon:56108
LOTUS DOI:10.1021/NP800751J
Fischerella ambigua
NCBITaxon:56108
CYANOMETDB DOI:10.1021/np800751j

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001126 Fischerella ambigua UTEX 1903
NCBITaxon:230521
CLUSTER_DEMONSTRATED genbank:KF664586.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001126MIBIG4

This page is generated from data/natural_products/alkaloids/ambiguine-k-isonitrile.yaml, which is generated from the committed inventories. Neither is edited by hand.