aspernidine A
CHEBI:74221 EXACT SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
A member of the class of isoindoles that is isoindolin-1-one which is substituted at positions 4, 5 and 6 by hydroxy, triprenyloxy and methoxy groups, respectively. The alkaloid was isolated from the model fungus Aspegillus nidulans.
Structure
| Standard InChIKey | PHOZASLNSDMYGR-VZRGJMDUSA-N |
|---|---|
| SMILES | CC(=CCC/C(=C/CC/C(=C/COC1=C(C=C2C(=C1O)CNC2=O)OC)/C)/C)C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:45359507 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
SOURCE_ASSERTION | mibig:BGC0001722 | DOI:10.1038/ja.2010.46 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Aspergillus nidulans NCBITaxon:162425 |
LOTUS | DOI:10.1038/JA.2010.46 |
| Aegiceras corniculatum NCBITaxon:59970 |
LOTUS | DOI:10.1016/J.PHYTOCHEM.2011.04.014 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001722 | Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
CLUSTER_UNSTATED | genbank:BN001306.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001722 | MIBIG | 3 |
| CHEBI:74221 | CHEBI | 3-star |
This page is generated from data/natural_products/alkaloids/aspernidine-a.yaml, which is generated from the committed inventories. Neither is edited by hand.