aspyridone B
CHEBI:64705 EXACT SEEDED
2-Pyridone carrying as substituents a branched dimethylhexanoyl group, a hydroxy group and a 3,4-dihydroxyphenyl group at C-3, -4 and -5 respectively. Secondary metabolite produced by Aspergillus spp.
Structure
| Standard InChIKey | SFWFNVOTIWZXMZ-QWRGUYRKSA-N |
|---|---|
| SMILES | CC[C@H](C)C[C@H](C)C(=O)C1=C(C(=CNC1=O)C2=CC(=C(C=C2)O)O)O |
| Stereochemistry | fully defined |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
SOURCE_ASSERTION | mibig:BGC0000959 | PMID:17369821 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Aspergillus nidulans NCBITaxon:162425 |
LOTUS | DOI:10.1038/NCHEMBIO869 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000959 | Aspergillus nidulans FGSC A4 NCBITaxon:227321 |
CLUSTER_DEMONSTRATED | genbank:BN001305.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000959 | MIBIG | 5 |
| CHEBI:64705 | CHEBI | 3-star |
This page is generated from data/natural_products/alkaloids/aspyridone-b.yaml, which is generated from the committed inventories. Neither is edited by hand.