NaturalProductMech

AT2433-A1

naturalproductmech:mibig-6c1bd93a9d MINTED SEEDED

Structure

Standard InChIKeyCGQSZYLXZOKJEJ-VYCQBBBDSA-N
SMILESCN[C@H]1CO[C@H](C[C@@H]1O)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1OC)N1C2=C3NC4=C(C=CC=C4)C3=C3C(=O)N(C)C(=O)C3=C2C2=C1C(Cl)=CC=C2
Stereochemistryfully defined
Cross-referencesnpatlas:NPA011993

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Actinomadura melliaura
NCBITaxon:360723
SOURCE_ASSERTION mibig:BGC0000809 PMID:16873021

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Actinomadura melliaura
NCBITaxon:360723
LOTUS DOI:10.1021/ACS.JNATPROD.5B00429
Actinomadura melliaura
NCBITaxon:360723
LOTUS DOI:10.7164/ANTIBIOTICS.42.1547

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000809 Actinomadura melliaura
NCBITaxon:360723
CLUSTER_UNSTATED genbank:DQ297453.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000809MIBIG3

This page is generated from data/natural_products/alkaloids/at2433-a1.yaml, which is generated from the committed inventories. Neither is edited by hand.