aurachin C

CHEBI:90888 EXACT SEEDED antibacterial

A C-type aurachin that is quinolin-4-one which is substituted by a hydroxy group at positions 1, a methyl group at position 2, and a triprenyl group at position 3.

Structure

Standard InChIKey	FIHXCHBEHLCXEG-YEFHWUCQSA-N
SMILES	CC1=C(C(=O)C2=CC=CC=C2N1O)C/C=C(\C)/CC/C=C(\C)/CCC=C(C)C
Stereochemistry	fully defined
Cross-references	npatlas:NPA006757

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, terpene, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Streptomyces sp. NCBITaxon:1931	SOURCE_ASSERTION	mibig:BGC0002591	PMID:28420868

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Streptomyces NCBITaxon:1883	LOTUS	DOI:10.1038/JA.2017.50
Stigmatella aurantiaca NCBITaxon:41	LOTUS	DOI:10.1021/NP8003084
Stigmatella aurantiaca NCBITaxon:41	LOTUS	DOI:10.7164/ANTIBIOTICS.40.258
Stigmatella aurantiaca Sg a15 NCBITaxon:675526	CHEBI	PMID:3106289
Stigmatella erecta NCBITaxon:83460	LOTUS	DOI:10.1021/NP800325Z

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0002591	Streptomyces sp. NCBITaxon:1931	CLUSTER_UNSTATED	genbank:KY810820.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

AntibioticMech — CHEBI:90888 (same structure, same inchikey)

Provenance

Source concept	Source	Version
BGC0002591	MIBIG	2
CHEBI:90888	CHEBI	3-star

This page is generated from data/natural_products/alkaloids/aurachin-c.yaml, which is generated from the committed inventories. Neither is edited by hand.