aurachin D
naturalproductmech:mibig-3421b5e37a MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | JHMLNOXMSHURLQ-YEFHWUCQSA-N |
|---|---|
| SMILES | CC(C)=CCC\C(C)=C\CC\C(C)=C\CC1=C(C)NC2=CC=CC=C2C1=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA019718, pubchem:6124753 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, terpene, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Stigmatella aurantiaca Sg a15 NCBITaxon:675526 |
SOURCE_ASSERTION | mibig:BGC0001343 | PMID:26473393 |
| Streptomyces sp. NCBITaxon:1931 |
SOURCE_ASSERTION | mibig:BGC0002591 | PMID:28420868 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1038/JA.2017.50 |
| Stigmatella aurantiaca NCBITaxon:41 |
LOTUS | DOI:10.1021/NP8003084 |
| Stigmatella aurantiaca NCBITaxon:41 |
LOTUS | DOI:10.7164/ANTIBIOTICS.40.258 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001343 | Stigmatella aurantiaca Sg a15 NCBITaxon:675526 |
CLUSTER_UNSTATED | genbank:AM404078.2 |
| mibig:BGC0002591 | Streptomyces sp. NCBITaxon:1931 |
CLUSTER_UNSTATED | genbank:KY810820.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001343, BGC0002591. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001343 | MIBIG | 3 |
| BGC0002591 | MIBIG | 2 |
This page is generated from data/natural_products/alkaloids/aurachin-d.yaml, which is generated from the committed inventories. Neither is edited by hand.