NaturalProductMech

borregomycin A

naturalproductmech:mibig-d95e84a818 MINTED SEEDED

Structure

Standard InChIKeyUFDOKWNWOJAMHK-OCESARCHSA-N
SMILESO=C1[C@]2(OC)N3C(C4=C([C@]2(OC)C(N1C)=O)C5=CC=C(Cl)C=C5N4)(O)C(C6=CC=C(Cl)C=C63)=O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 0

None. The compound has a characterized gene cluster whose host NCBI does not name, which for an uncultured symbiont is the honest state — see the discussion below.

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001335 not named CLUSTER_DEMONSTRATED genbank:JX827455.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

unnamed-producer — No producer claim is written from BGC0001335, which gives NCBITaxon:77133 (uncultured bacterium — shared by every unplaced bacterium), because the taxon names no single organism. The cluster is kept: a characterized locus is an origin assertion whether or not its host has a name, and for a compound from an uncultured symbiont that is the honest state. Name the producer if the primary literature does.

Provenance

Source conceptSourceVersion
BGC0001335MIBIG5

This page is generated from data/natural_products/alkaloids/borregomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.