closthioamide
naturalproductmech:mibig-0018095d97 MINTED SEEDED
Structure
| Standard InChIKey | UBZKZUDCUOZCCY-UHFFFAOYSA-N |
|---|---|
| SMILES | C1=CC(=CC=C1C(=S)NCCC(=S)NCCC(=S)NCCCNC(=S)CCNC(=S)CCNC(=S)C2=CC=C(C=C2)O)O |
| Stereochemistry | fully defined |
| Cross-references | pubchem:135937227 |
Filing pathway
Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Ruminiclostridium cellulolyticum H10 NCBITaxon:394503 |
SOURCE_ASSERTION | mibig:BGC0001891 | DOI:10.1002/anie.201807970 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Clostridium cellulolyticum NCBITaxon:1521 |
LOTUS | DOI:10.1002/ANGE.200906114 |
| Clostridium cellulolyticum NCBITaxon:1521 |
LOTUS | DOI:10.1002/ANIE.200906114 |
| Ruminiclostridium cellulolyticum NCBITaxon:1521 |
LOTUS | DOI:10.1002/ANIE.201807970 |
| Clostridium cellulolyticum NCBITaxon:1521 |
LOTUS | DOI:10.1002/EJOC.201001695 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001891 | Ruminiclostridium cellulolyticum H10 NCBITaxon:394503 |
CLUSTER_UNSTATED | genbank:CP001348.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001891 | MIBIG | 3 |
This page is generated from data/natural_products/alkaloids/closthioamide.yaml, which is generated from the committed inventories. Neither is edited by hand.