NaturalProductMech

dixiamycin A

naturalproductmech:mibig-abcb3d7c73 MINTED SEEDED

Structure

Standard InChIKeyCPQSJHUUXUXWOT-IPPPMHIGSA-N
SMILESC[C@]12CC[C@@H]([C@@]([C@@H]1CCC3=CC4=C(C=C23)C5=CC=CC=C5N4N6C7=CC=CC=C7C8=C6C=C9CC[C@@H]1[C@@](C9=C8)(CC[C@@H]([C@@]1(C)C(=O)O)O)C)(C)C(=O)O)O
Stereochemistryfully defined

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is terpene, other, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. HKI0576
NCBITaxon:995841
BGC_CHARACTERIZED mibig:BGC0000665 DOI:10.1002/anie.201204087
Streptomyces sp. HKI0576
NCBITaxon:995841
BGC_CHARACTERIZED mibig:BGC0000665 DOI:10.1002/anie.201204087

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces xinghaiensis
NCBITaxon:1038928
LOTUS DOI:10.1007/S00253-018-9337-2
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1002/ANIE.201204087
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1002/EJOC.201200599

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0000665 Streptomyces sp. HKI0576
NCBITaxon:995841
CLUSTER_DEMONSTRATED genbank:HE815466.1
mibig:BGC0000665 Streptomyces sp. HKI0576
NCBITaxon:995841
CLUSTER_DEMONSTRATED genbank:HE815466.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000665MIBIG5
BGC0000665MIBIG5

This page is generated from data/natural_products/alkaloids/dixiamycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.