NaturalProductMech

endophenazine A

naturalproductmech:mibig-383a92387c MINTED SEEDED

Structure

Standard InChIKeyWLQXISHGKXGNFV-UHFFFAOYSA-N
SMILESCC(C)=CCC1=CC=CC2=NC3=CC=CC(C(O)=O)=C3N=C12
Stereochemistryfully defined
Cross-referencesnpatlas:NPA015622, pubchem:10039975

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces anulatus
NCBITaxon:1892
BGC_CHARACTERIZED mibig:BGC0001080 PMID:22509222

Occurrences 4

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces cinnamonensis
NCBITaxon:1961
LOTUS DOI:10.1021/JO0703404
Streptomyces anulatus
NCBITaxon:1892
LOTUS DOI:10.3762/BJOC.8.57
Streptomyces anulatus
NCBITaxon:1892
LOTUS DOI:10.7164/ANTIBIOTICS.55.794
Streptomyces anulatus
NCBITaxon:1892
LOTUS DOI:10.7164/ANTIBIOTICS.55.801

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001080 Streptomyces anulatus
NCBITaxon:1892
CLUSTER_DEMONSTRATED genbank:FN178498.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001080MIBIG5

This page is generated from data/natural_products/alkaloids/endophenazine-a.yaml, which is generated from the committed inventories. Neither is edited by hand.