NaturalProductMech

ergovaline

naturalproductmech:mibig-12dcf2ebce MINTED SEEDED

Structure

Standard InChIKeyBGHDUTQZGWOQIA-VQSKNWBGSA-N
SMILESCC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C)NC(=O)[C@H]4CN([C@@H]5CC6=CNC7=CC=CC(=C67)C5=C4)C)O
Stereochemistryfully defined

Filing pathway

Alkaloids — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Epichloe festucae var. lolii
NCBITaxon:73839
SOURCE_ASSERTION mibig:BGC0000348 PMID:17308187

Occurrences 8

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Cenchrus echinatus
NCBITaxon:173841
LOTUS DOI:10.1021/NP50071A021
Festuca arundinacea
NCBITaxon:4606
LOTUS DOI:10.1021/JF00064A038
Festuca arundinacea
NCBITaxon:4606
LOTUS DOI:10.1021/JF00080A023
Claviceps purpurea
NCBITaxon:5111
LOTUS DOI:10.1139/V79-263
Epichloe typhina
NCBITaxon:5113
LOTUS DOI:10.1021/JF00105A055
Festuca rubra
NCBITaxon:52153
LOTUS DOI:10.1021/JF00064A038
Festuca rubra
NCBITaxon:52153
LOTUS DOI:10.1021/JF00080A023
Epichloe festucae var. lolii
NCBITaxon:73839
LOTUS DOI:10.1128/AEM.00257-07

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000348 Epichloe festucae var. lolii
NCBITaxon:73839
CLUSTER_UNSTATED genbank:EF125025.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000348MIBIG4

This page is generated from data/natural_products/alkaloids/ergovaline.yaml, which is generated from the committed inventories. Neither is edited by hand.